Novel tissue regeneration strategies are constantly being developed worldwide. Research
on bone regeneration is noteworthy, as many promising new approaches have been …

Bones are metabolically active organs. Their reconstruction is crucial for the proper
functioning of the skeletal system during bone growth and remodeling, fracture healing, and …

Cytokines play a pivotal role in maintaining bone homeostasis. Osteoclasts (OCs), the sole
bone resorbing cells, are regulated by numerous cytokines. Macrophage colony-stimulating …

Osteoblasts, which are bone-forming cells, play pivotal roles in bone modeling and
remodeling. Osteoblast differentiation, also known as osteoblastogenesis, is orchestrated by …

Sepsis remains a major cause of death. Cytokines interact closely with each other and play
a crucial role in the progression of sepsis. We focussed on the associations of a cytokine …

The Calcium-Sensing Receptor (CaSR) is a member of the class C of G-proteins coupled
receptors (GPCRs), it plays a pivotal role in calcium homeostasis by directly controlling …

Background The best‐known symptoms of coeliac disease are related to the gastrointestinal
tract, but the disease may also present with various systemic manifestations outside the …

The function of B cells in osteoblast (OB) dysfunction in rheumatoid arthritis (RA) has not
been well-studied. Here we show that B cells are enriched in the subchondral and endosteal …

Osteoporosis is a frequent complication of chronic inflammatory diseases and increases in
the pro-inflammatory cytokines make an important contribution to bone loss by promoting …

Osteoarthritis (OA) is the most common joint disorder, with a social and financial burden that
is expected to increase in the coming years. Currently, there are no effective medications to …