Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which
is of great significance to tissue development. ECM in muscle fiber niche consists of three …

Muscular Dystrophies (MDs) are a group of rare inherited genetic muscular pathologies
encompassing a variety of clinical phenotypes, gene mutations and mechanisms of disease …

Skeletal muscle accounts for the largest proportion of human body mass, on average, and is
a key tissue in complex diseases and mobility. It is composed of several different cell and …

Ethnopharmacological relevance FZLFR was derived from a classic traditional Chinese
medicine recipe, the Shiquan-Dabu decoction. FZLFR is commonly used in clinical practice …

Large-scale muscle injury in humans initiates a complex regeneration process, as not only
the muscular, but also the vascular and neuro-muscular compartments have to be repaired …

Temperature strongly modulates muscle development and growth in ectothermic teleosts;
however, the underlying mechanisms remain largely unknown. In this study, primary cultures …

The extracellular matrix (ECM) plays a crucial role in regulating cellular behaviors and
functions. However, the impact of ECM topography on muscle cell adhesion and …

A body of literature supports the postulation that a persistent lipid metabolic imbalance
causes lipotoxicity,“an abnormal fat storage in the peripheral organs”. Hence, lipotoxicity …

Stem cell behavior is tightly regulated by spatiotemporal signaling from the niche, which is a
four-dimensional microenvironment that can instruct stem cells to remain quiescent, self …

Mechanical unloading can lead to homeostasis imbalance and severe muscle disease, in
which muscle atrophy was one of the disused diseases. However, there were limited …