Fluid accumulation syndrome in sepsis and septic shock: pathophysiology, relevance and treatment—a comprehensive review

CA Pfortmueller, W Dabrowski, R Wise… - Annals of intensive …, 2024 - Springer
In this review, we aimed to comprehensively summarize current literature on
pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with …

Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis

M Girardis, S David, R Ferrer, J Helms… - Intensive Care …, 2024 - Springer
The interplay between the immune system, coagulation, and endothelium is critical in
regulating the host response to infection. However, in sepsis and other critical illnesses, a …

Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock

MBN Kjær, TS Meyhoff, P Sivapalan, A Granholm… - Intensive care …, 2023 - Springer
Purpose To assess long-term outcomes of restrictive versus standard intravenous (IV) fluid
therapy in adult intensive care unit (ICU) patients with septic shock included in the European …

Sepsis management in the cardiac intensive care unit

Y Zhang, MT McCurdy, J Ludmir - Journal of Cardiovascular …, 2023 - mdpi.com
Septic shock management in the cardiac intensive care unit (CICU) is challenging due to the
complex interaction of pathophysiology between vasodilatory and cardiogenic shock …

Fluid boluses and infusions in the early phase of resuscitation from septic shock and sepsis-induced hypotension: a retrospective report and outcome analysis from a …

A Messina, M Albini, N Samuelli, A Brunati… - Annals of Intensive …, 2024 - Springer
Background Fluid administration is the first line treatment in intensive care unit (ICU) patients
with sepsis and septic shock. While fluid boluses administration can be titrated by predicting …

Blood pressure response index and clinical outcomes in patients with septic shock: a multicenter cohort study

Y Chen, H Jiang, Y Wei, Y Qiu, L Su, J Chen, X Ding… - …, 2024 - thelancet.com
Background Sepsis is a leading cause of mortality in intensive care units and vasoactive
drugs are widely used in septic patients. The cardiovascular response of septic shock …

Moderate IV fluid resuscitation is associated with decreased sepsis mortality

KA Corl, MM Levy, AL Holder, IS Douglas… - Critical Care …, 2024 - journals.lww.com
OBJECTIVES: Significant practice variation exists in the amount of resuscitative IV fluid
given to patients with sepsis. Current research suggests equipoise between a tightly …

Fluid management in the septic peri-operative patient

P Nasa, R Wise, MLNG Malbrain - Current Opinion in Critical …, 2024 - journals.lww.com
Optimization of peri-operative fluid management is crucial for improving surgical outcomes
and reducing postoperative complications in patients with sepsis. Individualized and GDFT …

Understanding fluid dynamics and renal perfusion in acute kidney injury management

A Messina, M Calatroni, G Castellani… - Journal of Clinical …, 2024 - Springer
Acute kidney injury (AKI) is associated with an increased risk of morbidity, mortality, and
healthcare expenditure, posing a major challenge in clinical practice, and affecting about …

Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock—Bayesian analyses of the CLASSIC trial

P Sivapalan, TS Meyhoff, PB Hjortrup… - Acta …, 2024 - Wiley Online Library
Background The CLASSIC trial assessed the effects of restrictive versus standard
intravenous (IV) fluid therapy in adult intensive care unit (ICU) patients with septic shock …