Develo** dietary interventions as therapy for cancer

SR Taylor, JN Falcone, LC Cantley… - Nature Reviews …, 2022 - nature.com
Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic
alterations and degree of interaction with systemic hormones and metabolites. These …

Biosynthesis of milk fat, protein, and lactose: roles of transcriptional and posttranscriptional regulation

JS Osorio, J Lohakare, M Bionaz - Physiological genomics, 2016 - journals.physiology.org
The demand for high-quality milk is increasing worldwide. The efficiency of milk synthesis
can be improved by taking advantage of the accumulated knowledge of the transcriptional …

Alterations of milk oligosaccharides in mothers with gestational diabetes mellitus impede colonization of beneficial bacteria and development of RORγt+ Treg cell …

X Li, X Ning, B Rui, Y Wang, Z Lei, D Yu, F Liu… - Gut …, 2023 - Taylor & Francis
Gestational diabetes mellitus (GDM) is an increasing public health concern that significantly
increases the risk of early childhood allergic diseases. Altered maternal milk glycobiome …

Gene networks driving bovine mammary protein synthesis during the lactation cycle

M Bionaz, JJ Loor - Bioinformatics and biology insights, 2011 - journals.sagepub.com
A crucial role for both insulin and mTOR in the regulation of milk protein synthesis is
emerging. Bovine mammary biopsies harvested during late-pregnancy through end of …

Biological underpinnings of breastfeeding challenges: the role of genetics, diet, and environment on lactation physiology

S Lee, SL Kelleher - American Journal of Physiology …, 2016 - journals.physiology.org
Lactation is a dynamic process that has evolved to produce a complex biological fluid that
provides nutritive and nonnutritive factors to the nursing offspring. It has long been assumed …

[HTML][HTML] Causes of low milk supply: the roles of estrogens, progesterone, and related external factors

X **, SL Perrella, CT Lai, NL Taylor, DT Geddes - Advances in Nutrition, 2024 - Elsevier
Low milk supply (LMS) poses a significant challenge to exclusive and continued
breastfeeding, affecting∼ 10% to 15% of mothers. Milk production is intricately regulated by …

Human milk extracellular vesicle miRNA expression and associations with maternal characteristics in a population-based cohort from the Faroe Islands

A Kupsco, D Prada, D Valvi, L Hu, MS Petersen… - Scientific reports, 2021 - nature.com
Human milk plays a critical role in infant development and health, particularly in cognitive,
immune, and cardiometabolic functions. Milk contains extracellular vesicles (EVs) that can …

[HTML][HTML] Does insulin explain the relation between maternal obesity and poor lactation outcomes? An overview of the literature

LA Nommsen-Rivers - Advances in Nutrition, 2016 - Elsevier
It is well established that obese women are at increased risk of delayed lactogenesis and
short breastfeeding duration, but the underlying causal contributors remain unclear. This …

Evolution of lactation: ancient origin and extreme adaptations of the lactation system

CM Lefèvre, JA Sharp… - Annual review of genomics …, 2010 - annualreviews.org
Lactation, an important characteristic of mammalian reproduction, has evolved by exploiting
a diversity of strategies across mammals. Comparative genomics and transcriptomics …

Impacts of heat stress-induced oxidative stress on the milk protein biosynthesis of dairy cows

Z Guo, S Gao, J Ouyang, L Ma, D Bu - Animals, 2021 - mdpi.com
Simple Summary Heat stress (HS) of dairy cows affects milk protein synthesis partially due to
a decline in appetite and dry matter intake (DMI). Several published studies indicate that HS …