[HTML][HTML] Bromelain, a Group of Pineapple Proteolytic Complex Enzymes (Ananas comosus) and Their Possible Therapeutic and Clinical Effects. A Summary

C Varilla, M Marcone, L Paiva, J Baptista - Foods, 2021 - mdpi.com
Bromelain is a complex combination of multiple endopeptidases of thiol and other
compounds derived from the pineapple fruit, stem and/or root. Fruit bromelain and stem …

[HTML][HTML] Beneficial properties of bromelain

P Hikisz, J Bernasinska-Slomczewska - Nutrients, 2021 - mdpi.com
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

Pineapple peel extract incorporated poly (vinyl alcohol)-corn starch film for active food packaging: Preparation, characterization and antioxidant activity

P Kumar, R Tanwar, V Gupta, A Upadhyay… - International Journal of …, 2021 - Elsevier
This research study explores the fabrication of polyvinyl alcohol (PVOH) and corn starch
(ST) with pineapple peel extract (PPE) as a natural antioxidant agent, which is an abundant …

Recovery of high value-added compounds from pineapple, melon, watermelon and pumpkin processing by-products: An overview

X Rico, B Gullón, JL Alonso, R Yáñez - Food Research International, 2020 - Elsevier
Nowadays, fruit and vegetable industries generate huge amounts of under-utilized by-
products with a great economic potential. The processing by-products account from 25 up to …

Bromelain: an overview of industrial application and purification strategies

ZIM Arshad, A Amid, F Yusof, I Jaswir, K Ahmad… - Applied microbiology …, 2014 - Springer
This review highlights the use of bromelain in various applications with up-to-date literature
on the purification of bromelain from pineapple fruit and waste such as peel, core, crown …

Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

Development of L-asparaginase biobetters: current research status and review of the desirable quality profiles

LP Brumano, FVS da Silva, TA Costa-Silva… - … in bioengineering and …, 2019 - frontiersin.org
L-Asparaginase (ASNase) is a vital component of the first line treatment of acute
lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to afflict over …

Stability, purification, and applications of bromelain: A review

LC de Lencastre Novaes, AF Jozala… - Biotechnology …, 2016 - Wiley Online Library
Bromelain is a cysteine protease found in pineapple tissue. Because of its anti‐inflammatory
and anti‐cancer activities, as well as its ability to induce apoptotic cell death, bromelain has …

Bromelain surface modification increases the diffusion of silica nanoparticles in the tumor extracellular matrix

A Parodi, SG Haddix, N Taghipour, S Scaria… - ACS …, 2014 - ACS Publications
Tumor extracellular matrix (ECM) represents a major obstacle to the diffusion of therapeutics
and drug delivery systems in cancer parenchyma. This biological barrier limits the efficacy of …

[HTML][HTML] Bromelain and nisin: The natural antimicrobials with high potential in biomedicine

U Jančič, S Gorgieva - Pharmaceutics, 2021 - mdpi.com
Infectious diseases along with various cancer types are among the most significant public
health problems and the leading cause of death worldwide. The situation has become even …