Immune checkpoint blockade (ICB) has heralded a new era in cancer therapy. Research
into the mechanisms underlying response to ICB has predominantly focused on T cells; …

Many scientific investigations of photometric galaxy surveys require redshift estimates,
whose uncertainty properties are best encapsulated by photometric redshift (photo-z) …

TCR stimulation triggers Ca2+ signals that are critical for T cell function and immunity.
Several pore-forming α and auxiliary β subunits of voltage-gated Ca2+ channels (VGCC) …

To advance the measurement of distributed neuronal population representations of targeted
motor actions on single trials, we developed an optical method (COSMOS) for tracking …

Genomes store information at scales beyond the linear nucleotide sequence, which impacts
genome function at the level of an individual, while influences on populations and long-term …

Our understanding of the Universe has profited from deliberate targeted studies of known
phenomena, as well as from serendipitous unexpected discoveries, such as the discovery of …

Inhibiting the enzymes carbonic anhydrase I (CA I) and carbonic anhydrase II (CA II)
presents a potential avenue for addressing nervous system ailments such as glaucoma and …

In the ocean, viruses impact microbial mortality, regulate biogeochemical cycling, and alter
the metabolic potential of microbial lineages. At deep-sea hydrothermal vents, abundant …

Animals use olfactory receptors to navigate mates, food, and danger. However, for complex
olfactory systems, it is unknown what proportion of primary olfactory sensory neurons can …

Animal behaviour alternates between stochastic exploration and goal-directed actions,
which are generated by the underlying neural dynamics. Previously, we demonstrated that …