Image-based profiling for drug discovery: due for a machine-learning upgrade?

SN Chandrasekaran, H Ceulemans, JD Boyd… - Nature Reviews Drug …, 2021 - nature.com
Image-based profiling is a maturing strategy by which the rich information present in
biological images is reduced to a multidimensional profile, a collection of extracted image …

Smart hydrogels in tissue engineering and regenerative medicine

S Mantha, S Pillai, P Khayambashi, A Upadhyay… - Materials, 2019 - mdpi.com
The field of regenerative medicine has tremendous potential for improved treatment
outcomes and has been stimulated by advances made in bioengineering over the last few …

Curvature in biological systems: its quantification, emergence, and implications across the scales

B Schamberger, R Ziege, K Anselme… - advanced …, 2023 - Wiley Online Library
Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

Hydrogel-forming algae polysaccharides: From seaweed to biomedical applications

M Beaumont, R Tran, G Vera, D Niedrist… - …, 2021 - ACS Publications
With the increasing growth of the algae industry and the development of algae biorefinery,
there is a growing need for high-value applications of algae-extracted biopolymers. The …

A comprehensive review on droplet-based bioprinting: Past, present and future

H Gudapati, M Dey, I Ozbolat - Biomaterials, 2016 - Elsevier
Droplet-based bioprinting (DBB) offers greater advantages due to its simplicity and agility
with precise control on deposition of biologics including cells, growth factors, genes, drugs …

Silk fibroin as biomaterial for bone tissue engineering

J Melke, S Midha, S Ghosh, K Ito, S Hofmann - Acta biomaterialia, 2016 - Elsevier
Silk fibroin (SF) is a fibrous protein which is produced mainly by silkworms and spiders. Its
unique mechanical properties, tunable biodegradation rate and the ability to support the …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

[HTML][HTML] Extracellular matrix: a dynamic microenvironment for stem cell niche

F Gattazzo, A Urciuolo, P Bonaldo - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Background Extracellular matrix (ECM) is a dynamic and complex environment
characterized by biophysical, mechanical and biochemical properties specific for each …

Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate

MJ Dalby, N Gadegaard, ROC Oreffo - Nature materials, 2014 - nature.com
Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Materials as stem cell regulators

WL Murphy, TC McDevitt, AJ Engler - Nature materials, 2014 - nature.com
The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …