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Neurogenesis in the aging brain
Adult neurogenesis is the process of producing new neurons from neural stem cells (NSCs)
for integration into the brain circuitry. Neurogenesis occurs throughout life in the ventricular …
for integration into the brain circuitry. Neurogenesis occurs throughout life in the ventricular …
Multiple effects of growth hormone in the body: is it really the hormone for growth?
J Devesa, C Almengló… - Clinical Medicine Insights …, 2016 - journals.sagepub.com
In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …
and its putative role in the longitudinal growth of an organism. We conclude that the …
Neurogenesis in the normal ageing hippocampus: a mini-review
New neurons are continuously generated and added to neural circuits in the adult brain.
However, increasing age imposes changes in neural progenitor cells and their …
However, increasing age imposes changes in neural progenitor cells and their …
Mechanisms of enhanced quiescence in neural stem cell aging
AJ Audesse, AE Webb - Mechanisms of ageing and development, 2020 - Elsevier
The maintenance of neural stem cell function is vital to ensure neurogenesis throughout
adulthood. During aging, there is a significant reduction in adult neurogenesis that …
adulthood. During aging, there is a significant reduction in adult neurogenesis that …
Lasting adaptations in social behavior produced by social disruption and inhibition of adult neurogenesis
Research on social instability has focused on its detrimental consequences, but most people
are resilient and respond by invoking various co** strategies. To investigate cellular …
are resilient and respond by invoking various co** strategies. To investigate cellular …
New neurons in aging brains: molecular control by small non-coding RNAs
Adult neurogenesis generates functional neurons from neural stem cells present in specific
brain regions. It is largely confined to two main regions: the subventricular zone of the lateral …
brain regions. It is largely confined to two main regions: the subventricular zone of the lateral …
Exercise and environment as an intervention for neonatal alcohol effects on hippocampal adult neurogenesis and learning
Neonatal alcohol exposure impairs cognition and learning in adulthood and permanently
damages the hippocampus. Wheel running (WR) improves hippocampus-associated …
damages the hippocampus. Wheel running (WR) improves hippocampus-associated …
Distinguishing adaptive plasticity from vulnerability in the aging hippocampus
DT Gray, CA Barnes - Neuroscience, 2015 - Elsevier
Hippocampal circuits are among the best described networks in the mammalian brain,
particularly with regard to the alterations that arise during normal aging. Decades of …
particularly with regard to the alterations that arise during normal aging. Decades of …
Heterogeneities in intrinsic excitability and frequency-dependent response properties of granule cells across the blades of the rat dentate gyrus
The dentate gyrus (DG), the input gate to the hippocampus proper, is anatomically
segregated into three different sectors, namely, the suprapyramidal blade, the crest region …
segregated into three different sectors, namely, the suprapyramidal blade, the crest region …
Effect of Nrf2 loss on senescence and cognition of tau-based P301S mice
R Riordan, W Rong, Z Yu, G Ross, J Valerio… - Geroscience, 2023 - Springer
Cellular senescence may contribute to chronic inflammation involved in the progression of
age-related diseases such as Alzheimer's disease (AD), and its removal prevents cognitive …
age-related diseases such as Alzheimer's disease (AD), and its removal prevents cognitive …