Plant flavonoids on oxidative stress-mediated kidney inflammation

S Alsawaf, F Alnuaimi, S Afzal, RM Thomas… - Biology, 2022 - mdpi.com
Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …

Chrysin a promising anticancer agent: Recent perspectives

M Shahbaz, H Naeem, M Imran… - … Journal of Food …, 2023 - Taylor & Francis
Honey, propolis, and passionflower contain a flavone known as chrysin. Researchers are
studying chrysin to prove its potential to stop cancer cells growth. Chrysin cancer therapeutic …

Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes

N Akaras, C Gur, S Kucukler, FM Kandemir - Chemico-biological …, 2023 - Elsevier
Arsenic is widely available in the environment and arsenic toxicity is a public health problem
of serious concern worldwide. Zingerone is a promising phytochemical with various …

Chemopreventive effects of hesperidin against paclitaxel-induced hepatotoxicity and nephrotoxicity via amendment of Nrf2/HO-1 and caspase-3/Bax/Bcl-2 signaling …

C Gur, FM Kandemir, C Caglayan, E Satıcı - Chemico-biological …, 2022 - Elsevier
Paclitaxel (PTX) is a widely used chemotherapeutic drug particularly effective against lung,
breast, and ovarian cancer, though its usefulness is limited due to its multi-organ toxicity …

Investigation of the effects of hesperidin administration on abamectin‐induced testicular toxicity in rats through oxidative stress, endoplasmic reticulum stress …

C Gur, O Kandemir, FM Kandemir - Environmental Toxicology, 2022 - Wiley Online Library
In this study, the potential effects of hesperidin (HES) on chronic toxicity caused by
abamectin (ABM) in the testicular tissue were investigated through oxidative stress …

Beneficial effects of Chrysin on Cadmium‐induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO‐1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling …

H Şimşek, N Akaras, C Gür, S Küçükler, FM Kandemir - Gene, 2023 - Elsevier
Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …

Rutin protects rat liver and kidney from sodium valproate-induce damage by attenuating oxidative stress, ER stress, inflammation, apoptosis and autophagy

FM Kandemir, M Ileriturk, C Gur - Molecular biology reports, 2022 - Springer
Background The present study investigated the effects of rutin (RUT), which has various
biological and pharmacological properties, on liver and kidney damage caused by histone …

Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating …

A Yardim, FM Kandemir, S Ozdemir, S Kucukler… - Neurotoxicology, 2020 - Elsevier
In the present study, the protective effects of quercetin on peripheral neurotoxicity caused by
vincristine, which is used effectively in the treatment of various types of cancers, were …

The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats

HS Semis, FM Kandemir, O Kaynar, T Dogan… - Life Sciences, 2021 - Elsevier
Paclitaxel (PTX), which is widely used in the treatment of solid tumors, leads to dose
limitation because it causes peripheral neuropathy. This study was conducted to evaluate …

Evaluation of therapeutic effects of quercetin against Achilles tendinopathy in rats via oxidative stress, inflammation, apoptosis, autophagy, and metalloproteinases

HS Semis, C Gur, M Ileriturk… - … American journal of …, 2022 - journals.sagepub.com
Background: Achilles tendinopathy, seen in athletes and manual labor workers, is an
inflammatory condition characterized by chronic tendon pain. Owing to the toxicity that …