Tau in neurodegenerative diseases: molecular mechanisms, biomarkers, and therapeutic strategies
The deposition of abnormal tau protein is characteristic of Alzheimer's disease (AD) and a
class of neurodegenerative diseases called tauopathies. Physiologically, tau maintains an …
class of neurodegenerative diseases called tauopathies. Physiologically, tau maintains an …
[HTML][HTML] White matter damage and degeneration in traumatic brain injury
Traumatic brain injury (TBI) is a complex condition that can resolve over time but all too often
leads to persistent symptoms, and the risk of poor patient outcomes increases with aging …
leads to persistent symptoms, and the risk of poor patient outcomes increases with aging …
Neuropathologic and clinical findings in young contact sport athletes exposed to repetitive head impacts
Importance Young contact sport athletes may be at risk for long-term neuropathologic
disorders, including chronic traumatic encephalopathy (CTE). Objective To characterize the …
disorders, including chronic traumatic encephalopathy (CTE). Objective To characterize the …
Risk of chronic traumatic encephalopathy in rugby union is associated with length of playing career
There is concern over late, adverse brain health outcomes associated with contact sports
participation, with high neurodegenerative disease risk reported in studies of former …
participation, with high neurodegenerative disease risk reported in studies of former …
Update on modifiable risk factors for Alzheimer's disease and related dementias
While greater and higher quality epidemiological and experimental evidence is needed to
unequivocally confirm their causal link with ADRD and/or unravel the underlying …
unequivocally confirm their causal link with ADRD and/or unravel the underlying …
Cellular senescence as a key contributor to secondary neurodegeneration in traumatic brain injury and stroke
Traumatic brain injury (TBI) and stroke pose major health challenges, impacting millions of
individuals globally. Once considered solely acute events, these neurological conditions are …
individuals globally. Once considered solely acute events, these neurological conditions are …
A review of brain regions and associated post-concussion symptoms
The human brain is an exceptionally complex organ that is comprised of billions of neurons.
Therefore, when a traumatic event such as a concussion occurs, somatic, cognitive …
Therefore, when a traumatic event such as a concussion occurs, somatic, cognitive …
Alzheimer's Disease-Related Dementias Summit 2022: national research priorities for the investigation of post-traumatic brain injury Alzheimer's disease and related …
K Dams-O'Connor, HO Awwad, S Hoffman… - Journal of …, 2023 - liebertpub.com
Traumatic Brain Injury (TBI) is a risk factor for Alzheimer's disease and Alzheimer's disease
related dementias (AD/ADRD) and otherwise classified post-traumatic neurodegeneration …
related dementias (AD/ADRD) and otherwise classified post-traumatic neurodegeneration …
Chronic traumatic encephalopathy in a female ex-professional Australian rules footballer
Chronic traumatic encephalopathy (CTE) is a neuropathological diagnosis of degenerative
brain disease characterized by neuronal accumulation of hyperphosphorylated tau (p-tau) …
brain disease characterized by neuronal accumulation of hyperphosphorylated tau (p-tau) …
Innovative insights into traumatic brain injuries: biomarkers and new pharmacological targets
S Silvestro, I Raffaele, A Quartarone… - International Journal of …, 2024 - mdpi.com
A traumatic brain injury (TBI) is a major health issue affecting many people across the world,
causing significant morbidity and mortality. TBIs often have long-lasting effects, disrupting …
causing significant morbidity and mortality. TBIs often have long-lasting effects, disrupting …