Biosynthesis and regulation of phenylpropanoids in plants

Y Deng, S Lu - Critical reviews in plant sciences, 2017 - Taylor & Francis
Phenylpropanoids are a large class of plant secondary metabolites derived from aromatic
amino acids phenylalanine in most plants or tyrosine in partial monocots. It mainly includes …

Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms

PK Ajikumar, K Tyo, S Carlsen, O Mucha… - Molecular …, 2008 - ACS Publications
Terpenoids represent a diverse class of molecules that provide a wealth of opportunities to
address many human health and societal issues. The expansive array of structures and …

Metabolic engineering of flavonoids in plants and microorganisms

Y Wang, S Chen, O Yu - Applied microbiology and biotechnology, 2011 - Springer
Over 9,000 flavonoid compounds have been found in various plants, comprising one of the
largest families of natural products. Flavonoids are an essential factor in plant interactions …

Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases

I Abe, H Morita - Natural product reports, 2010 - pubs.rsc.org
Covering: 2002 to 2009 This review covers recent advances in structure and function studies
on the chalcone synthase (CHS) superfamily of plant type III polyketide synthases (PKSs) …

De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae

F Koopman, J Beekwilder, B Crimi… - Microbial cell …, 2012 - Springer
Background Flavonoids comprise a large family of secondary plant metabolic intermediates
that exhibit a wide variety of antioxidant and human health-related properties. Plant …

Synergetic Engineering of Multiple Pathways for De Novo (2S)-Naringenin Biosynthesis in Saccharomyces cerevisiae

H Li, W Ma, W Wang, S Gao, X Shan… - … Sustainable Chemistry & …, 2023 - ACS Publications
(2S)-Naringenin is a high-value flavonoid precursor with different biological properties.
However, current metabolic engineering strategies do not fully use intracellular carbon …

Sustainable production of natural phenolics for functional food applications

R Mark, X Lyu, JJL Lee, R Parra-Saldívar… - Journal of Functional …, 2019 - Elsevier
Phenolics are a class of plant-derived natural secondary metabolites with good anticancer,
anti-inflammatory, antimicrobial and antioxidant activities. In addition to being natural health …

Optimization of a heterologous pathway for the production of flavonoids from glucose

CNS Santos, M Koffas, G Stephanopoulos - Metabolic engineering, 2011 - Elsevier
The development of efficient microbial processes for the production of flavonoids has been a
metabolic engineering goal for the past several years, primarily due to the purported health …

Highly active and specific tyrosine ammonia-lyases from diverse origins enable enhanced production of aromatic compounds in bacteria and Saccharomyces …

CB Jendresen, SG Stahlhut, M Li… - Applied and …, 2015 - journals.asm.org
Phenylalanine and tyrosine ammonia-lyases form cinnamic acid and p-coumaric acid, which
are precursors of a wide range of aromatic compounds of biotechnological interest. Lack of …