Ki-67 protein has been widely used as a proliferation marker for human tumor cells for
decades. In recent studies, multiple molecular functions of this large protein have become …

Type VI secretion is a newly described mechanism for protein transport across the cell
envelope of Gram-negative bacteria. Components that have been partially characterised …

The microbial communities inhabiting the root interior of healthy plants, as well as the
rhizosphere, which consists of soil particles firmly attached to roots, engage in symbiotic …

In this study, we used cryoelectron microscopy to determine the structures of the Flotillin
protein complex, part of the Stomatin, Prohibitin, Flotillin, and HflK/C (SPFH) superfamily …

To counteract the continuous exposure of cells to agents that damage DNA, cells have
evolved complex regulatory networks called checkpoints to sense DNA damage and …

What do we know about Ki-67, apart from its usefulness as a cell proliferation biomarker in
histopathology? Discovered in 1983, the protein and its regulation of expression and …

The genus Mycobacterium is best known for its two major pathogenic species, M.
tuberculosis and M. leprae, the causative agents of two of the world's oldest diseases …

Living cells display complex signal processing behaviors, many of which are mediated by
networks of proteins specialized for signal transduction. Here we focus on the question of …

Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating
cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review …

Abstract MRE11, RAD50 and NBS1 form a highly conserved protein complex (the MRE11
complex) that is involved in the detection, signalling and repair of DNA damage. We identify …