Antitumor agents based on metal–organic frameworks

P Gao, Y Chen, W Pan, N Li, Z Liu… - Angewandte Chemie, 2021 - Wiley Online Library
Metal–organic frameworks (MOFs) hold great promise for biomedical applications owing to
their unique properties. The porous structures make MOFs excellent candidates for the …

The mechanisms of nanoparticle delivery to solid tumours

LNM Nguyen, W Ngo, ZP Lin, S Sindhwani… - Nature Reviews …, 2024 - nature.com
Nanoparticles for the detection and treatment of cancer have suffered from limited clinical
translation. A key problem has been the lack of understanding of the mechanisms of …

Interface Assembly of Polymer Networks on Metal–Organic Frameworks for the Engineering of Functional Nanoparticles

Y Tian, Z Gao, M Li, M Hu, J Hao, J Cui - Chemistry of Materials, 2023 - ACS Publications
We report a versatile approach for the engineering of functional polymer nanoparticles (NPs)
with tunable sizes, stiffness, and responsiveness via templating zeolitic imidazolate …

Modular Metal‐Quinone Networks with Tunable Architecture and Functionality

QZ Zhong, JJ Richardson, Y Tian, H Tian… - Angewandte Chemie …, 2023 - Wiley Online Library
Nanostructured materials with tunable structures and functionality are of interest in diverse
areas. Herein, metal ions are coordinated with quinones through metal‐acetylacetone …

Advances in metal-based nano drugs and diagnostic probes for tumor

J Ding, Z He, Y Zhai, L Ye, J Ji, X Yang… - Coordination Chemistry …, 2024 - Elsevier
Tumors, particularly malignant ones, seriously impact human health. Numerous studies
have demonstrated the exceptional potential of metal-based nanosystems, both as drugs …

Lecithin/chitosan nanoparticle drug carrier improves anti-tumor efficacy of Monascus pigment rubropunctatin

S Ning, C Wang, L Zhao, J Yang, X Shi… - International journal of …, 2023 - Elsevier
Rubropunctatin, a metabolite isolated from the fungi of the genus Monascus, is a natural
lead compound applied for the suppression of tumors with good anti-cancer activity …

Biomaterials in Drug Delivery: Advancements in Cancer and Diverse Therapies

A Drabczyk, S Kudłacik-Kramarczyk… - International Journal of …, 2024 - mdpi.com
Nano-sized biomaterials are innovative drug carriers with nanometric dimensions. Designed
with biocompatibility in mind, they enable precise drug delivery while minimizing side …

Supramolecular 3 in 1: A Lubrication and Co-Delivery System for Synergistic Advanced Osteoarthritis Therapy

MM Chen, Y Li, Y Zhu, WC Geng, FY Chen, JJ Li… - ACS …, 2024 - ACS Publications
The complexity, heterogeneity, and drug resistance of diseases necessitate a shift in
therapeutic paradigms from monotherapy to combination therapy, which could augment …

Synergistic effects of anticancer drug delivered via nanoporous zeolitic imidazolate frameworks: implications for tumor therapy

H Liu, D Qi, Y Luo, H Bao, T Li, K Sun… - ACS Applied Nano …, 2023 - ACS Publications
Due to the resistance and toxicity of existing anticancer agents, it forces people to
continuously develop antitumor drugs that can overcome these side effects. Herein, we …

Revisiting recent unusual drug-DNA complex structures: implications for cancer and neurological disease diagnostics and therapeutics

R Satange, AB Rode, MH Hou - Bioorganic & Medicinal Chemistry, 2022 - Elsevier
DNA plays a crucial role in various biological processes such as protein production,
replication, recombination etc. by adopting different conformations. Targeting these …