HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome

C Belizna, F Pregnolato, S Abad, J Alijotas-Reig… - Autoimmunity …, 2018 - Elsevier
The relapse rate in antiphospholipid syndrome (APS) remains high, ie around 20%–21% at
5 years in thrombotic APS and 20–28% in obstetrical APS [2, 3]. Hydroxychloroquine (HCQ) …

Antiphospholipid syndrome

M Khamashta, M Taraborelli, S Sciascia… - Best practice & research …, 2016 - Elsevier
Antiphospholipid syndrome (APS) is an autoimmune condition characterized by the
occurrence of thrombosis (arterial and/or venous), often multiple, and/or pregnancy …

Classic and global hemostasis testing in pregnancy and during pregnancy complications

FI Ataullakhanov, EM Koltsova… - … in Thrombosis and …, 2016 - thieme-connect.com
Pregnancy is associated with a significant procoagulant shift in the hemostatic system
balance as well as other metabolic changes. Pregnancy can thereby provoke manifestation …

Antiphospholipid syndrome: Diagnosis and management in the obstetric patient

E Arslan, DW Branch - Best practice & research Clinical obstetrics & …, 2020 - Elsevier
Antiphospholipid syndrome (APS) is a rare condition clinically characterized by thrombotic
events or pregnancy complications and confirmed by one or more repeatedly positive …

Primary antiphospholipid syndrome and antiphospholipid syndrome associated to systemic lupus: are they different entities?

C Belizna, L Stojanovich, JW Cohen-Tervaert… - Autoimmunity …, 2018 - Elsevier
Primary antiphospholipid syndrome (PAPS) and antiphospholipid syndrome associated to
lupus (SAPS) have several overlap** characteristics. As systemic manifestations are also …

Presence of immune complexes of IgG/IgM bound to B2-glycoprotein I is associated with non-criteria clinical manifestations in patients with antiphospholipid syndrome

D Pérez, L Stojanovich, L Naranjo… - Frontiers in …, 2018 - frontiersin.org
Background: Antiphospholipid syndrome (APS) is an acquired autoimmune disorder defined
by the presence of both clinical (thromboembolic events or pregnancy morbidity) and …

Serological evolution in women with positive antiphospholipid antibodies

L Riancho-Zarrabeitia, G Daroca, P Muñoz… - Seminars in arthritis and …, 2017 - Elsevier
Objectives To explore the clinical and serological course of fertile women with positive
antiphospholipid (aPL), and the factors and therapeutic implications associated with aPL …

Antiphospholipid antibodies overlap** in isolated neurological syndrome and multiple sclerosis: neurobiological insights and diagnostic challenges

C D'Angelo, O Franch, L Fernández-Paredes… - Frontiers in Cellular …, 2019 - frontiersin.org
Antiphospholipid syndrome (APS) is characterized by arterial and venous thrombosis,
pregnancy morbidity and fetal loss caused by pathogenic autoantibodies directed against …

Hughes syndrome and epilepsy: when to test for antiphospholipid antibodies?

MHA Noureldine, G Harifi, A Berjawi, AA Haydar… - Lupus, 2016 - journals.sagepub.com
Epilepsy and seizures are reported among the neurological manifestations of
antiphospholipid syndrome (APS) at a prevalence rate of approximately 8%, which is nearly …

Antiphospholipid antibodies: their origin and development

KJ Lackner, N Müller-Calleja - Antibodies, 2016 - mdpi.com
Antiphospholipid antibodies (aPL) are a hallmark of the antiphospholipid syndrome (APS),
which is the most commonly acquired thrombophilia. To date there is consensus that aPL …