Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Aptamers are single-stranded nucleic acids that bind and recognize targets much like
antibodies. Recently, aptamers have garnered increased interest due to their unique …

Molecular diagnosis of COVID-19 primarily relies on the detection of RNA of the SARS-CoV-
2 virus, the causative infectious agent of the pandemic. Reverse transcription polymerase …

The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

The availability of sensors able to rapidly detect SARS-CoV-2 directly in biological fluids in a
single step would allow performing massive diagnostic testing to track in real time and …

The combination of 2D MXenes with high affinity aptamers has resulted in the development
of innovative aptasensing approaches for food/water safety and clinical diagnosis. Aptamers …

Rapid, mass diagnosis of the coronavirus disease 2019 (COVID-19) is critical to stop the
ongoing infection spread. The two standard screening methods to confirm the severe acute …

We developed a new surface-enhanced Raman scattering (SERS)-based aptasensor
platform capable of quantifying severe acute respiratory syndrome coronavirus 2 (SARS …

We report a simple and rapid saliva‐based SARS‐CoV‐2 antigen test that utilizes a newly
developed dimeric DNA aptamer, denoted as DSA1N5, that specifically recognizes the spike …

Coined three decades ago, the term aptamer and directed evolution have now reached their
maturity. The concept that nucleic acid could modulate the activity of target protein as ligand …