Objectives Efforts towards achieving durable resin–dentin bonds have been made for
decades, including the understanding of the mechanisms underlying hybrid layer (HL) …

Objective Success in adhesive dentistry means long lasting restorations. However, there is
substantial evidence that this ideal objective is not always achieved. Current research in this …

This literature-based OPINION PAPER reflects in an introductory historical perspective on
the rapid advancement of dental adhesive technology. Past and current techniques to bond …

Dentin can be described as a biological composite with collagen matrix embedded with
nanosized hydroxyapatite mineral crystallites. Matrix metalloproteinases (MMPs) and …

Objective Endogenous dentin collagenolytic enzymes, matrix metalloproteinases (MMPs)
and cysteine cathepsins, are responsible for the time-dependent hydrolysis of collagen …

Recent advances regarding the caries process indicate that ecological phenomena induced
by bacterial acid production tilt the de-and remineralization balance of the dental hard …

OBJECTIVES: Contemporary adhesives lose their bond strength to dentin regardless of the
bonding system used. This loss relates to the hydrolysis of collagen matrix of the hybrid …

In dentin bonding, contemporary dental adhesive systems rely on formation of the hybrid
layer, a biocomposite containing dentin collagen and polymerized resin adhesive. They are …

Objectives The biomodification of dentin is a biomimetic approach, mediated by bioactive
agents, to enhance and reinforce the dentin by locally altering the biochemistry and …

This study aimed to identify the role of crosslinking agents in the resin–dentin bond strength
(BS) when used as modifiers in adhesives or pretreatments to the dentin surface through a …