Although rigidity and jamming transitions have been widely studied in physics and material
science, their importance in a number of biological processes, including embryo …

Cells come in a variety of shapes that most often underlie their functions. Regulation of cell
morphogenesis implies that there are mechanisms for shape sensing that still remain poorly …

Activity and autonomous motion are fundamental in living and engineering systems. This
has stimulated the new field of'active matter'in recent years, which focuses on the physical …

INTRODUCTION Within each animal species, embryonic development is highly
reproducible, ensuring the faithful production of a complex organism with precisely arranged …

Oriented cell division patterns tissues by modulating cell position and fate. While cell
geometry, junctions, cortical tension, and polarity are known to control division orientation …

The way in which interactions between mechanics and biochemistry lead to the emergence
of complex cell and tissue organization is an old question that has recently attracted …

During pre‐implantation development, the mammalian zygote transforms into the blastocyst,
the structure that will implant the embryo in the maternal uterus. Consisting of a squamous …

Planar spindle orientation is critical for epithelial tissue organization and is generally
instructed by the long cell-shape axis or cortical polarity domains. We introduced mouse …

In early embryos, microtubules form star-shaped aster structures that can measure up to
hundreds of micrometres in size, and move at high speeds to find the geometrical centre of …

Nuclear size plays pivotal roles in gene expression, embryo development, and disease. A
central hypothesis in organisms ranging from yeast to vertebrates is that nuclear size scales …