Emerging nanotechnology for Alzheimer's disease: From detection to treatment

N Song, S Sun, K Chen, Y Wang, H Wang… - Journal of Controlled …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), one of the most common chronic neurodegenerative
diseases, is characterized by memory impairment, synaptic dysfunction, and character …

Electrochemical immunosensors developed for amyloid-beta and tau proteins, leading biomarkers of Alzheimer's disease

A Sharma, L Angnes, N Sattarahmady, M Negahdary… - Biosensors, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurological disease and a serious cause of
dementia, which constitutes a threat to human health. The clinical evidence has found that …

In pursuit of degenerative brain disease diagnosis: Dementia biomarkers detected by DNA aptamer-attached portable graphene biosensor

TA Bodily, A Ramanathan, S Wei, A Karkisaval… - Proceedings of the …, 2023 - pnas.org
Dementia is a brain disease which results in irreversible and progressive loss of cognition
and motor activity. Despite global efforts, there is no simple and reliable diagnosis or …

Cerebrospinal fluid: A specific biofluid for the biosensing of Alzheimer's diseases biomarkers

A Mirzaie, H Nasrollahpour, B Khalilzadeh… - TrAC Trends in …, 2023 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder with an
irreversible, progressive, and untreatable nature that causes progressive deterioration, loss …

[HTML][HTML] The major hypotheses of Alzheimer's disease: related nanotechnology-based approaches for its diagnosis and treatment

C Cáceres, B Heusser, A Garnham, E Moczko - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is a well-known chronic neurodegenerative disorder that leads to
the progressive death of brain cells, resulting in memory loss and the loss of other critical …

Amyloid Detection in Neurodegenerative Diseases through MOFs

K Maru, A Singh, R Jangir, KK Jangir - Journal of Materials Chemistry …, 2024 - pubs.rsc.org
Neurodegenerative diseases (amyloid diseases such as Alzheimer's and Parkinson's),
stemming from protein misfolding and aggregation, encompass a spectrum of disorders with …

[HTML][HTML] An electrochemical sensing platform based on gold nanostars for the detection of Alzheimer's disease marker Aβ oligomers (Aβo)

P Wang, S Chen, Y Guan, Y Li, A Jiamali - Alexandria Engineering Journal, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the
accumulation of amyloid-beta (Aβ) peptides in the brain. Among the different forms of Aβ …

Alzheimer's disease diagnosis in the preclinical stage: Normal aging or dementia

F Marvi, YH Chen, M Sawan - IEEE reviews in biomedical …, 2024 - ieeexplore.ieee.org
Alzheimer's disease (AD) progressively impairs the memory and thinking skills of patients,
resulting in a significant global economic and social burden each year. However, diagnosis …

Application of Pt@ ZIF-8 nanocomposite-based electrochemical biosensor for sensitive diagnosis of tau protein in Alzheimer's disease patients

F Chakari-Khiavi, A Mirzaie, B Khalilzadeh, H Yousefi… - Scientific reports, 2023 - nature.com
Alzheimer's disease (AD) is a progressive brain disorder characterized by the ongoing
decline of brain functions. Studies have revealed the detrimental effects of …

Ultrasensitive capacitance sensor to detect amyloid-beta 1-40 in human serum using supramolecular recognition of β-CD/RGO/ITO micro-disk electrode

HTN Le, D Kim, S Cho - Talanta, 2022 - Elsevier
In this paper, we developed a new ultrasensitive capacitance sensor for detection of amyloid
beta 1-40 (aβ40) protein (one of Alzheimer's disease core biomarkers) in human serum …