Chimeric antigen receptor macrophage (CAR-MΦ) represents a significant advancement in
immunotherapy, especially for treating solid tumors where traditional CAR-T therapies face …

Аbstract With increasing incidence and geography, cancer is one of the leading causes of
death, reduced quality of life and disability worldwide. Principal progress in the development …

The tumor microenvironment (TME) in ovarian cancer (OC) has much greater complexity
than previously understood. In response to aggressive pro-angiogenic stimulus, blood …

Extracellular matrix (ECM) plays a pivotal and dynamic role in the construction of tumor
microenvironment (TME), becoming the focus in cancer research and treatment. Multiple cell …

Cuproptosis is a newly identified form of cell death induced by excessive copper (Cu)
accumulation within cells. Mechanistically, cuproptosis results from Cu-induced aggregation …

Multidrug resistance (MDR) poses a significant obstacle to effective cancer treatment, and
the tumor microenvironment (TME) is crucial for MDR development and reversal. The TME …

Lung cancer is the leading cause of cancer-related death worldwide. KRAS mutations are
the most common oncogenic alterations found in lung cancer. Unfortunately, treating KRAS …

HDAC inhibitors, which can inhibit the activity of HDAC enzymes, have been extensively
studied in tumor immunotherapy and have shown potential therapeutic effects in cancer …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

Breast cancer is the second-leading cause of cancer death among women in the United
States. Triple-negative breast cancer (TNBC), a subtype of breast cancer, is an aggressive …