Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement

C Salomon, S Das, U Erdbrügger, R Kalluri… - Endocrine …, 2022 - academic.oup.com
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …

The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets

M Ghafourian, R Mahdavi, Z Akbari Jonoush… - Cell Communication and …, 2022 - Springer
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

[HTML][HTML] Exosomes as messengers between mother and fetus in pregnancy

L Czernek, M Düchler - International Journal of Molecular Sciences, 2020 - mdpi.com
The ability of exosomes to transport different molecular cargoes and their ability to influence
various physiological factors is already well known. An exciting area of research explores …

The oral glucose tolerance test—is it time for a change?—a literature review with an emphasis on pregnancy

D Bogdanet, P O'Shea, C Lyons, A Shafat… - Journal of clinical …, 2020 - mdpi.com
Globally, gestational diabetes (GDM) is increasing at an alarming rate. This increase is
linked to the rise in obesity rates among women of reproductive age. GDM poses a major …

Extracellular vesicles are dynamic regulators of maternal glucose homeostasis during pregnancy

HC Zierden, R Marx-Rattner, KD Rock… - Scientific reports, 2023 - nature.com
Homeostatic regulation of the maternal milieu during pregnancy is critical for maternal and
fetal health. The placenta facilitates critical communication between maternal and fetal …

Gestational diabetes mellitus—innovative approach to prediction, diagnosis, management, and prevention of future NCD—mother and offspring

HD McIntyre, A Kapur, H Divakar, M Hod - Frontiers in endocrinology, 2020 - frontiersin.org
Gestational diabetes mellitus (GDM) is the commonest medical complication of pregnancy.
The association of GDM with immediate pregnancy complications including excess fetal …

Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes

LB James‐Allan, FJ Rosario, K Barner, A Lai… - The FASEB …, 2020 - Wiley Online Library
The mechanisms underpinning maternal metabolic adaptations to a healthy pregnancy and
in gestational diabetes mellitus (GDM) remain poorly understood. We hypothesized that …

Placental exosomes as biomarkers for maternal diseases: current advances in isolation, characterization, and detection

CM Nguyen, M Sallam, MS Islam, K Clack, N Soda… - ACS …, 2023 - ACS Publications
Serving as the interface between fetal and maternal circulation, the placenta plays a critical
role in fetal growth and development. Placental exosomes are small membrane-bound …

Human placenta exosomes: biogenesis, isolation, composition, and prospects for use in diagnostics

EE Burkova, SE Sedykh, GA Nevinsky - International Journal of Molecular …, 2021 - mdpi.com
Exosomes are 40–100 nm nanovesicles participating in intercellular communication and
transferring various bioactive proteins, mRNAs, miRNAs, and lipids. During pregnancy, the …

Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

S Nair, D Guanzon, N Jayabalan, A Lai… - Journal of translational …, 2021 - Springer
Background Gestational diabetes mellitus (GDM) is a serious public health issue affecting 9–
15% of all pregnancies worldwide. Recently, it has been suggested that extracellular …