Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission

G Livingston, J Huntley, KY Liu, SG Costafreda… - The Lancet, 2024 - thelancet.com
Executive summary The 2024 update of the Lancet Commission on dementia provides new
hopeful evidence about dementia prevention, intervention, and care. As people live longer …

Primary stroke prevention worldwide: translating evidence into action

MO Owolabi, AG Thrift, A Mahal, M Ishida… - The Lancet Public …, 2022 - thelancet.com
Stroke is the second leading cause of death and the third leading cause of disability
worldwide and its burden is increasing rapidly in low-income and middle-income countries …

TRP (transient receptor potential) ion channel family: Structures, biological functions and therapeutic interventions for diseases

M Zhang, Y Ma, X Ye, N Zhang, L Pan… - Signal Transduction and …, 2023 - nature.com
Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …

US FDA approved drugs from 2015–June 2020: a perspective

P Bhutani, G Joshi, N Raja, N Bachhav… - Journal of Medicinal …, 2021 - ACS Publications
In the present work, we report compilation and analysis of 245 drugs, including small and
macromolecules approved by the US FDA from 2015 until June 2020. Nearly 29% of the …

[HTML][HTML] Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study …

JD Steinmetz, KM Seeher, N Schiess… - The Lancet …, 2024 - thelancet.com
Background Disorders affecting the nervous system are diverse and include
neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions …

Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization–Lancet Neurology Commission

VL Feigin, MO Owolabi, F Abd-Allah… - The Lancet …, 2023 - thelancet.com
Executive summary Stroke is the second leading cause of death worldwide. The burden of
disability after a stroke is also large, and is increasing at a faster pace in low-income and …

From diagnosis to treatment: recent advances in patient-friendly biosensors and implantable devices

P Li, GH Lee, SY Kim, SY Kwon, HR Kim, S Park - ACS nano, 2021 - ACS Publications
Patient-friendly medical diagnostics and treatments have been receiving a great deal of
interest due to their rapid and cost-effective health care applications with minimized risk of …

Advances in neurodegenerative diseases

J Van Schependom, M D'haeseleer - Journal of clinical medicine, 2023 - mdpi.com
Neurological disorders are the leading cause of physical and cognitive disability across the
globe, currently affecting approximately 15% of the worldwide population [1]. Absolute …

[HTML][HTML] AAV vectors applied to the treatment of CNS disorders: Clinical status and challenges

L Kang, S **, J Wang, Z Lv, C **n, C Tan… - Journal of Controlled …, 2023 - Elsevier
In recent years, adeno-associated virus (AAV) has become the most important vector for
central nervous system (CNS) gene therapy. AAV has already shown promising results in …

[HTML][HTML] Optical imaging and spectroscopy for the study of the human brain: status report

H Ayaz, WB Baker, G Blaney, DA Boas… - …, 2022 - spiedigitallibrary.org
This report is the second part of a comprehensive two-part series aimed at reviewing an
extensive and diverse toolkit of novel methods to explore brain health and function. While …