Context-dependent functions of pattern recognition receptors in cancer
SM Man, BJ Jenkins - Nature Reviews Cancer, 2022 - nature.com
The immune system plays a critical role in sha** all facets of cancer, from the early
initiation stage through to metastatic disease and resistance to therapy. Our understanding …
initiation stage through to metastatic disease and resistance to therapy. Our understanding …
NLRP3 inflammasome activation in cancer: a double-edged sword
S Hamarsheh, R Zeiser - Frontiers in immunology, 2020 - frontiersin.org
Inflammation is involved in tumor development and progression as well as antitumor
response to therapy. In the past decade, the crosstalk between inflammation, immunity, and …
response to therapy. In the past decade, the crosstalk between inflammation, immunity, and …
The hallmarks of flavonoids in cancer
LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …
foods and beverages with known biological activity in cells. From the modulation of …
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment
W Muhammad, J Zhu, Z Zhai, J **e, J Zhou, X Feng… - Acta biomaterialia, 2022 - Elsevier
The acute lung injury (ALI) is an inflammatory disorder associated with cytokine storm, which
activates various reactive oxygen species (ROS) signaling pathways and causes severe …
activates various reactive oxygen species (ROS) signaling pathways and causes severe …
NLRP3 as putative marker of ipilimumab-induced cardiotoxicity in the presence of hyperglycemia in estrogen-responsive and triple-negative breast cancer cells
V Quagliariello, M De Laurentiis, S Cocco… - International Journal of …, 2020 - mdpi.com
Hyperglycemia, obesity and metabolic syndrome are negative prognostic factors in breast
cancer patients. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment …
cancer patients. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment …
An epigenetic insight into NLRP3 inflammasome activation in inflammation-related processes
AB Raneros, CR Bernet, AB Flórez, B Suarez-Alvarez - Biomedicines, 2021 - mdpi.com
Aberrant NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome
activation in innate immune cells, triggered by diverse cellular danger signals, leads to the …
activation in innate immune cells, triggered by diverse cellular danger signals, leads to the …
Fusobacterium nucleatum induces MDSCs enrichment via activation the NLRP3 inflammosome in ESCC cells, leading to cisplatin resistance
M Liang, Y Liu, Z Zhang, H Yang, N Dai… - Annals of …, 2022 - Taylor & Francis
Background To analyse the regulatory effect of Fusobacterium nucleatum (Fn) on NOD-like
receptor protein 3 (NLRP3) and myeloid-derived suppressor cells (MDSCs) in oesophageal …
receptor protein 3 (NLRP3) and myeloid-derived suppressor cells (MDSCs) in oesophageal …
LINC01564 promotes the TMZ resistance of glioma cells by upregulating NFE2L2 expression to inhibit ferroptosis
C Luo, C Nie, Y Zeng, K Qian, X Li, X Wang - Molecular Neurobiology, 2022 - Springer
Glioma is the most common and malignant brain tumor with poor prognosis. We investigated
the effects of LINC01564 on temozolomide (TMZ) resistance of glioma cells. Quantitative …
the effects of LINC01564 on temozolomide (TMZ) resistance of glioma cells. Quantitative …
RETRACTED: Huaier extract suppresses non‐small cell lung cancer progression through activating NLRP3‐dependent pyroptosis
J **e, B Zhuan, H Wang, Y Wang, X Wang… - The Anatomical …, 2021 - Wiley Online Library
Recent studies have reported the anticancer activity of huaier extract in various human
malignancies. However, little is known about the effect of huaier extract in non‐small cell …
malignancies. However, little is known about the effect of huaier extract in non‐small cell …
Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury
W Muhammad, Y Zhang, J Zhu, J **e, S Wang… - Biomaterials …, 2023 - Elsevier
Bacterial infection causes lung inflammation and recruitment of several inflammatory factors
that may result in acute lung injury (ALI). During bacterial infection, reactive oxygen species …
that may result in acute lung injury (ALI). During bacterial infection, reactive oxygen species …