Immune checkpoint molecules are promising anticancer targets, among which therapeutic
antibodies targeting the PD-1/PD-L1 pathway have been widely applied to cancer treatment …

Systemic antiplatelet treatment represents a promising option to improve the therapeutic
outcomes and therapeutic efficacy of chemotherapy and immunotherapy due to the critical …

Photodynamic therapy (PDT), which utilizes type I photoreactions, has great potential as an
effective cancer treatment because of its hypoxia‐tolerant superiority over the commonly …

The brain is often described as an" immune-privileged" organ due to the presence of the
blood-brain-barrier (BBB), which limits the entry of immune cells. In general, intracranial …

Oxidative stress (OS) is a chemical imbalance between an oxidant and an antioxidant,
causing damage to redox signaling and control or causing molecular damage. Unbalanced …

Metastasis is the major cause of cancer deaths, and cancer cells evolve to adapt to various
tumor microenvironments, which hinders the treatment of tumor metastasis. Platelets play …

The treatment of non-small cell lung cancer (NSCLC) has changed dramatically with the
advent of immune checkpoint inhibitors (ICIs). Despite encouraging results, their efficacy …

The main role of platelets is to control bleeding and repair vascular damage via thrombosis.
They have also been implicated to promote tumor metastasis through platelet-tumor cell …

Background It remains controversial whether the platelet to lymphocyte ratio (PLR) serves as
a potential indicator for the efficacy of immunotherapy in advanced lung cancer. This meta …

It has been confirmed that platelets play a key role in tumorigenesis. Tumor-activated
platelets can recruit blood cells and immune cells to migrate, establish an inflammatory …