Nanoparticle drug delivery systems and their applications as targeted therapies for triple negative breast cancer

X Kong, Y Qi, X Wang, R Jiang, J Wang, Y Fang… - Progress in materials …, 2023‏ - Elsevier
The therapeutic effect of highly malignant triple negative breast cancer (TNBC) is negatively
affected by the formation of tumor cell resistant clone and the severe toxicity of …

Microneedle array systems for long-acting drug delivery

LK Vora, K Moffatt, IA Tekko, AJ Paredes… - European Journal of …, 2021‏ - Elsevier
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

Polymeric micelles: A novel drug delivery system for the treatment of breast cancer

A Chaudhuri, K Ramesh, DN Kumar, D Dehari… - Journal of Drug Delivery …, 2022‏ - Elsevier
Polymeric micelles have acquired quite an interest as an innovative drug delivery system for
the diagnosis and treatment of breast cancer, as they endeavour numerous benefits over the …

Nanomedicine in treatment of breast cancer–A challenge to conventional therapy

M Afzal, KS Alharbi, NK Alruwaili, FA Al-Abassi… - Seminars in cancer …, 2021‏ - Elsevier
Amongst the various types of cancer, breast cancer is a highly heterogeneous disease and
known as the leading cause of death among women globally. The extensive interdisciplinary …

Nanomedicine-based drug-targeting in breast cancer: pharmacokinetics, clinical progress, and challenges

M Rahman, O Afzal, SNMN Ullah, MY Alshahrani… - ACS …, 2023‏ - ACS Publications
Breast cancer (BC) is a malignant neoplasm that begins in the breast tissue. After skin
cancer, BC is the second most common type of cancer in women. At the end of 2040, the …

Exosomal delivery of cannabinoids against cancer

S Kaur, A Nathani, M Singh - Cancer letters, 2023‏ - Elsevier
Exosomes are extracellular vesicles (EVs) originating from endosomes that play a role in
cellular communication. These vesicles which mimic the parental cells that release them are …

Vitamin D3/phospholipid complex decorated caseinate nanomicelles for targeted delivery of synergistic combination therapy in breast cancer

MM Agwa, MM Abu-Serie, DA Abdelmonsif… - International Journal of …, 2021‏ - Elsevier
Targeted delivery of cytotoxic drugs has shown great potential in cancer therapy. In this light,
vitamin D3 (vit. D3)-coated micelles were fabricated to encapsulate the cytotoxic drug; …

Polymeric nanomaterials-based theranostic platforms for triple-negative breast cancer (TNBC) treatment

SR Baddam, S Ganta, S Nalla, C Banoth… - International Journal of …, 2024‏ - Elsevier
Breast cancer, the second leading global cause of death, affects 2.1 million women
annually, with an alarming 15 percent mortality rate. Among its diverse forms, Triple …

Exosome-based delivery nanoplatforms: next-generation theranostic platforms for breast cancer

Y Zheng, M Li, B Weng, H Mao, J Zhao - Biomaterials Science, 2022‏ - pubs.rsc.org
Breast cancer is the most frequent type of malignancy, and the leading cause of cancer-
related death in women across the globe. Exosomes are naturally derived 50–150 nm …

The role of Cannabidiol and tetrahydrocannabivarin to overcome doxorubicin resistance in MDA-MB-231 xenografts in athymic nude mice

AK Kalvala, R Nimma, A Bagde, SK Surapaneni… - Biochimie, 2023‏ - Elsevier
The significant resistance to currently available chemotherapeutics makes treatment for
TNBC a key clinical concern. Herein, we studied the anti-cancer potentials of synthetic …