To date, the treatable traits (TTs) approach has been applied in the context of managing
diagnosed diseases. TTs are clinical characteristics and risk factors that can be identified …

Epigenetic modifications are chemical groups in our DNA (and chromatin) that determine
which genes are active and which are shut off. Importantly, they integrate environmental …

Loss of Y chromosome (LOY) is the most commonly occurring post-zygotic (somatic)
mutation in male individuals. The past decade of research suggests that LOY has important …

Identification of body fluid stain at crime scene is one of the important tasks of forensic
evidence analysis. Currently, body fluid-specific CpGs detected by DNA methylation …

Introduction By recent estimates, 40% of children worldwide are exposed to second-hand
smoke (SHS), which has been associated with adverse health outcomes. While numerous …

The rapid rise in the availability and scale of scRNA-seq data needs scalable methods for
integrative analysis. Though many methods for data integration have been developed, few …

While the underlying mechanisms and assessment of clinical utility require further
investigation, the potential of epigenetics in sleep medicine is recognized. Future research …

Aim: Using the methylation level of miRNA genes to develop a prognostic model for patients
with hepatocellular carcinoma (HCC). Materials & methods: least absolute shrinkage and …

Alcohol use disorder (AUD) contributes significantly to the global burden of disease. The
susceptibility for AUD is mediated through an interaction of genetic risk factors and …

Background Recent studies have found that tobacco smoking is associated with fat
distribution, yet limited research has focused on its relationship with visceral adipose tissues …