Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease
We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …
strategy to improve respiratory and non-respiratory motor function in people with …
[HTML][HTML] Walking naturally after spinal cord injury using a brain–spine interface
H Lorach, A Galvez, V Spagnolo, F Martel, S Karakas… - Nature, 2023 - nature.com
A spinal cord injury interrupts the communication between the brain and the region of the
spinal cord that produces walking, leading to paralysis,. Here, we restored this …
spinal cord that produces walking, leading to paralysis,. Here, we restored this …
Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis
Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …
Transcutaneous spinal cord stimulation restores hand and arm function after spinal cord injury
Paralysis of the upper extremity severely restricts independence and quality of life after
spinal cord injury. Regaining control of hand and arm movements is the highest treatment …
spinal cord injury. Regaining control of hand and arm movements is the highest treatment …
Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury
Spinal cord injury (SCI) induces haemodynamic instability that threatens survival,–, impairs
neurological recovery,, increases the risk of cardiovascular disease,, and reduces quality of …
neurological recovery,, increases the risk of cardiovascular disease,, and reduces quality of …
Epidural spinal cord stimulation as an intervention for motor recovery after motor complete spinal cord injury
JT Hachmann, A Yousak, JJ Wallner… - Journal of …, 2021 - journals.physiology.org
Spinal cord injury (SCI) commonly results in permanent loss of motor, sensory, and
autonomic function. Recent clinical studies have shown that epidural spinal cord stimulation …
autonomic function. Recent clinical studies have shown that epidural spinal cord stimulation …
[HTML][HTML] Circuit reconstruction of newborn neurons after spinal cord injury in adult rats via an NT3-chitosan scaffold
Z Wang, H Duan, F Hao, P Hao, W Zhao, Y Gao… - Progress in …, 2023 - Elsevier
Abstract An implanted neurotrophin-3 (NT3)-chitosan scaffold can recruit endogenous
neural stem cells to migrate to a lesion region and differentiate into mature neurons after …
neural stem cells to migrate to a lesion region and differentiate into mature neurons after …
Non-invasive spinal cord electrical stimulation for arm and hand function in chronic tetraplegia: a safety and efficacy trial
Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …
Consequences of spinal cord injury on the sympathetic nervous system
MJ Wulf, VJ Tom - Frontiers in cellular neuroscience, 2023 - frontiersin.org
Spinal cord injury (SCI) damages multiple structures at the lesion site, including ascending,
descending, and propriospinal axons; interrupting the conduction of information up and …
descending, and propriospinal axons; interrupting the conduction of information up and …