[HTML][HTML] Mechanistic Insights on Microbiota-Mediated Development and Progression of Esophageal Cancer

KT Moe, KSW Tan - Cancers, 2024 - mdpi.com
Simple Summary Esophageal cancer (EC) is a serious global health problem with
increasing incidence and mortality rates. Aside from smoking and alcohol consumption …

Biomarkers of lymph node metastasis in esophageal cancer

N Wu, J Cai, J Jiang, Y Lin, X Wang, W Zhang… - Frontiers in …, 2024 - frontiersin.org
Esophageal cancer (EC) is among the most aggressive malignancies, ranking as the
seventh most prevalent malignant tumor worldwide. Lymph node metastasis (LNM) indicates …

Discovery of 2, 4-diaminopyrimidine derivatives as potent inhibitors of FAK capable of activating the Hippo pathway for the treatment of esophageal squamous cell …

X Wang, YR Li, J Wu, JB Niu, J Song… - European Journal of …, 2025 - Elsevier
In this work, we report the discovery of 2, 4-diaminopyrimidine derivatives bearing a urea
moiety as FAK inhibitors capable of activating the Hippo pathway in Esophageal Squamous …

A new NCL-targeting aptamer-drug conjugate as a promising therapy against esophageal cancer

X Zheng, Y Wang, H Duan, J Hou, S He - Journal of Nanobiotechnology, 2025 - Springer
Esophageal cancer (EC) is one of the most common highly malignant tumors of the digestive
system, with a poor prognosis under current treatment regimens. Nucleolin (NCL) is …

[HTML][HTML] Elevated MCL1 expression drives esophageal squamous cell carcinoma stemness and induces resistance to radiotherapy

J Chen, G Chen, X Fang, J Sun… - Journal of Thoracic …, 2024 - pmc.ncbi.nlm.nih.gov
Background Esophageal squamous cell carcinoma (ESCC) stands as the sixth most
common cause of cancer-related mortality on a global scale, with a strikingly high proportion …

Global, regional, and national burden of esophageal cancer: a systematic analysis of the Global Burden of Disease Study 2021

W **, K Huang, Z Ding, M Zhang, C Li, Z Yuan… - Biomarker …, 2025 - Springer
Background and objective Esophageal cancer (EC) is the seventh most prevalent cancer
globally and the sixth leading cause of cancer-related mortality. This study aimed to provide …

Surgery alone versus neoadjuvant chemoradiotherapy followed by surgery in patients with stage T2N0M0 esophageal cancer

Y Lin, SF Wang, HW Liang, Y Liu, W Huang, XB Pan - Scientific Reports, 2024 - nature.com
To compare the survival outcomes of patients with stage T2N0M0 esophageal cancer
treated with surgery alone versus those treated with neoadjuvant chemoradiotherapy …

Multimodality deep learning radiomics predicts pathological response after neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma

Y Liu, Y Wang, X Hu, X Wang, L Xue, Q Pang… - Insights into …, 2024 - Springer
Objectives This study aimed to develop and validate a deep-learning radiomics model using
CT, T2, and DWI images for predicting pathological complete response (pCR) in patients …

High antigen-presenting CAF levels correlate with reduced glycosaminoglycan biosynthesis-heparan sulfate/heparin metabolism in immune cells and poor prognosis …

S Wang, K Van Van, M Zheng, WL Chen… - International Journal of …, 2025 - Elsevier
In esophageal squamous cell carcinoma (ESCC), the tumor microenvironment (TME) is
characterized by a significant accumulation of cancer-associated fibroblasts (CAFs), which …

[HTML][HTML] Efficacy and Safety of Cryoablation in Barrett's Esophagus and Comparison with Radiofrequency Ablation: A Meta-Analysis

A Papaefthymiou, B Norton, A Telese, D Ramai… - Cancers, 2024 - mdpi.com
Simple Summary Cryoablation therapy is an emerging modality in the treatment of Barrett's
esophagus. Our systematic review collected data on this technique to provide evidence of its …