Consensus paper: towards a systems-level view of cerebellar function: the interplay between cerebellum, basal ganglia, and cortex

D Caligiore, G Pezzulo, G Baldassarre, AC Bostan… - The Cerebellum, 2017 - Springer
Despite increasing evidence suggesting the cerebellum works in concert with the cortex and
basal ganglia, the nature of the reciprocal interactions between these three brain regions …

Bidirectional learning in upbound and downbound microzones of the cerebellum

CI De Zeeuw - Nature Reviews Neuroscience, 2021 - nature.com
Over the past several decades, theories about cerebellar learning have evolved. A relatively
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …

Prediction signals in the cerebellum: beyond supervised motor learning

C Hull - elife, 2020 - elifesciences.org
While classical views of cerebellar learning have suggested that this structure predominantly
operates according to an error-based supervised learning rule to refine movements …

A neural circuit state change underlying skilled movements

MJ Wagner, J Savall, O Hernandez, G Mel, H Inan… - Cell, 2021 - cell.com
In motor neuroscience, state changes are hypothesized to time-lock neural assemblies
coordinating complex movements, but evidence for this remains slender. We tested whether …

Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions

W Heffley, EY Song, Z Xu, BN Taylor, MA Hughes… - Nature …, 2018 - nature.com
The prevailing model of cerebellar learning states that climbing fibers (CFs) are both driven
by, and serve to correct, erroneous motor output. However, this model is grounded largely in …

Purkinje-cell plasticity and cerebellar motor learning are graded by complex-spike duration

Y Yang, SG Lisberger - Nature, 2014 - nature.com
Behavioural learning is mediated by cellular plasticity, such as changes in the strength of
synapses at specific sites in neural circuits. The theory of cerebellar motor learning,, relies …

Cerebellum lecture: the cerebellar nuclei—core of the cerebellum

JM Kebschull, F Casoni, GG Consalez, D Goldowitz… - The Cerebellum, 2024 - Springer
The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

Cerebellar modules and their role as operational cerebellar processing units

R Apps, R Hawkes, S Aoki, F Bengtsson, AM Brown… - The Cerebellum, 2018 - Springer
The compartmentalization of the cerebellum into modules is often used to discuss its
function. What, exactly, can be considered a module, how do they operate, can they be …

Acquisition, extinction, and reacquisition of a cerebellar cortical memory trace

DA Jirenhed, F Bengtsson, G Hesslow - Journal of Neuroscience, 2007 - Soc Neuroscience
Associative learning in the cerebellum underlies motor memories and probably also
cognitive associations. Pavlovian eyeblink conditioning, a widely used experimental model …

Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning

JH Freeman, AB Steinmetz - Learning & memory, 2011 - learnmem.cshlp.org
Pavlovian eyeblink conditioning has been used extensively as a model system for
examining the neural mechanisms underlying associative learning. Delay eyeblink …