The initiation and maintenance of reproductive capacity in humans is dependent on pulsatile
secretion of the hypothalamic hormone GnRH. Congenital hypogonadotropic hypogonadism …

Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder caused by the
deficient production, secretion or action of gonadotropin-releasing hormone (GnRH), which …

Background Testosterone treatment in men with hypogonadism improves bone density and
quality, but trials with a sufficiently large sample and a sufficiently long duration to determine …

Objective: To formulate clinical practice guidelines for hormonal replacement in
hypopituitarism in adults. Participants: The participants include an Endocrine Society …

Abstract The Testosterone Trials (TTrials) were a coordinated set of seven placebo-
controlled, double-blind trials in 788 men with a mean age of 72 years to determine the …

Although first identified over 70 years ago, Klinefelter syndrome (KS) continues to pose
substantial diagnostic challenges, as many patients are still misdiagnosed, or remain …

Importance As men age, they experience decreased serum testosterone concentrations,
decreased bone mineral density (BMD), and increased risk of fracture. Objective To …

Osteoporosis is a skeletal disorder characterized by decreased mass and compromised
bone strength predisposing to an increased risk of fractures. Although idiopathic …

Objective: Our objective was to update the guidelines for the evaluation and treatment of
androgen deficiency syndromes in adult men published previously in 2006. Participants …

In contrast to other mental health disorders, eating disorders have a high prevalence of
concomitant medical complications. Specifically, patients suffering from anorexia nervosa …