RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
The use of RNA-based treatments in the field of cancer immunotherapy
M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
Microfluidic strategies for the isolation and profiling of exosomes
J Bai, X Wei, X Zhang, C Wu, Z Wang, M Chen… - TrAC Trends in …, 2023 - Elsevier
Exosomes are nanoscale extracellular vesicles carrying various cargos, which play a
significant rule in intercellular communication, disease diagnosis and treatment …
significant rule in intercellular communication, disease diagnosis and treatment …
Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
Technologies and standardization in research on extracellular vesicles
Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …
Advances in therapeutic applications of extracellular vesicles
Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles
secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid …
secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid …
New technologies for analysis of extracellular vesicles
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids
Extracellular vesicles (EVs) are small membranous vesicles that contain an abundant cargo
of different RNA species with specialized functions and clinical implications. Here, we …
of different RNA species with specialized functions and clinical implications. Here, we …
Exosomes and exosome-inspired vesicles for targeted drug delivery
The similarities between exosomes and liposomes, together with the high organotropism of
several types of exosomes, have recently prompted the development of engineered …
several types of exosomes, have recently prompted the development of engineered …