Marek's disease in chickens: a review with focus on immunology

N Boodhoo, A Gurung, S Sharif, S Behboudi - Veterinary research, 2016 - Springer
Abstract Marek's disease (MD), caused by Marek's disease virus (MDV), is a commercially
important neoplastic disease of poultry which is only controlled by mass vaccination …

Introduction to poultry vaccines and immunity

JM Sharma - Advances in veterinary medicine, 1999 - Elsevier
Poultry constitutes a vital segment of world agriculture. Yearly global production exceeds 30
billion birds. This number is expected to increase steadily in the foreseeable future. In the …

Pathogenesis of Marek's disease virus infection

BW Calnek - Marek's disease, 2001 - Springer
The term pathogenesis is most simply defined as the development of disease. Many
uncomplicated infectious diseases proceed in a direct fashion from infection to a specific …

Ancient chicken remains reveal the origins of virulence in Marek's disease virus

SR Fiddaman, EA Dimopoulos, O Lebrasseur… - Science, 2023 - science.org
The pronounced growth in livestock populations since the 1950s has altered the
epidemiological and evolutionary trajectory of their associated pathogens. For example …

Comparative analysis of Marek's disease virus (MDV) glycoprotein-, lytic antigen pp38-and transformation antigen Meq-encoding genes: association of meq mutations …

CE Shamblin, N Greene, V Arumugaswami… - Veterinary …, 2004 - Elsevier
Marek's disease (MD) is a highly contagious lymphoproliferative and demyelinating disorder
of chickens. MD is caused by Marek's disease virus (MDV), a cell-associated, acute …

Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding

M Koch, S Camp, T Collen, D Avila, J Salomonsen… - Immunity, 2007 - cell.com
Little is known about the structure of major histocompatibility complex (MHC) molecules
outside of mammals. Only one class I molecule in the chicken MHC is highly expressed …

Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus

Z **ng, KA Schat - Journal of virology, 2000 - Am Soc Microbiol
The replication of Marek's disease herpesvirus (MDV) and herpesvirus of turkeys (HVT) in
chicken embryo fibroblast (CEF) cultures was inhibited by the addition of S-nitroso-N …

Neoplastic diseases

V Nair, I Gimeno, J Dunn, G Zavala… - Diseases of …, 2020 - Wiley Online Library
This chapter deals primarily with the three most economically important virus‐induced
transmissible neoplastic diseases of poultry, namely: the herpesvirus‐induced Marek's …

Activated chicken gamma delta T cells are involved in protective immunity against marek's disease

A Matsuyama-Kato, B Shojadoost, N Boodhoo, S Raj… - Viruses, 2023 - mdpi.com
Gamma delta (γδ) T cells play a significant role in the prevention of viral infection and tumor
surveillance in mammals. Although the involvement of γδ T cells in Marek's disease virus …

Expression of cytokine genes in Marek's disease virus‐infected chickens and chicken embryo fibroblast cultures

Z **ng, KA Schat - Immunology, 2000 - Wiley Online Library
The role of cytokines in the pathogenesis and immunity of Marek's disease (MD), a
herpesvirus‐induced T‐cell lymphoma in chickens, is poorly understood. Two different …