Recent advances in intraocular sustained-release drug delivery devices

Y Cao, KE Samy, DA Bernards, TA Desai - Drug discovery today, 2019 - Elsevier
Highlights•We highlight polymeric materials used for long-acting intraocular drug
delivery.•We discuss design considerations for delivering small molecules and …

Clinical management algorithm of uveitis associated with juvenile idiopathic arthritis: interdisciplinary panel consensus

R Bou, A Adán, F Borrás, B Bravo, I Calvo… - Rheumatology …, 2015 - Springer
Uveitis associated with juvenile idiopathic arthritis (JIA) typically involves the anterior
chamber segment, follows an indolent chronic course, and presents a high rate of uveitic …

Slow-release dexamethasone in proliferative vitreoretinopathy: a prospective, randomized controlled clinical trial

PJ Banerjee, A Quartilho, C Bunce, W **ng, TM Zvobgo… - Ophthalmology, 2017 - Elsevier
Purpose To test the hypothesis that adjunctive slow-release dexamethasone implant
(Ozurdex; Allergan Inc, Irvine, CA) can improve the outcomes of vitreoretinal surgery for …

Multicenter study of intravitreal dexamethasone implant in noninfectious uveitis: indications, outcomes, and reinjection frequency

J Zarranz-Ventura, E Carreño, RL Johnston… - American journal of …, 2014 - Elsevier
Purpose To identify clinical outcomes and treatment patterns of intravitreal dexamethasone
implant (Ozurdex; Allergan, Inc) in noninfectious uveitis in the clinical setting. Design …

Uveitic macular edema

C Fardeau, E Champion, N Massamba, P LeHoang - Eye, 2016 - nature.com
Macular edema (ME) may complicate anterior, intermediate, and posterior uveitis, which
may be because of various infectious, neoplastic or autoimmune etiologies. BRB breakdown …

Pharmacokinetics of intravitreal anti-VEGF drugs in vitrectomized versus non-vitrectomized eyes

M Edington, J Connolly, NV Chong - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: The review aims to discuss effects of vitrectomy on pharmacokinetics of anti-
vascular endothelial growth factor (anti-VEGF) agents, and attempt to provide treatment …

Pharmacotherapy for uveitis: current management and emerging therapy

RJ Barry, QD Nguyen, RW Lee, PI Murray… - Clinical …, 2014 - Taylor & Francis
Uveitis, a group of conditions characterized by intraocular inflammation, is a major cause of
sight loss in the working population. Most uveitis seen in Western countries is noninfectious …

Update in treatment of uveitic macular edema

S Koronis, P Stavrakas, M Balidis… - Drug design …, 2019 - Taylor & Francis
Macular edema (ME) represents the most common cause for visual loss among uveitis
patients. The management of uveitic macular edema (UME) may be challenging, due to its …

Tocilizumab treatment for refractory uveitis-related cystoid macular edema

A Adán, M Mesquida, V Llorenç, G Espinosa… - Graefe's Archive for …, 2013 - Springer
Background This retrospective study investigated the efficacy of tocilizumab (TCZ), a fully
humanized antibody that binds both to soluble and membrane bound IL-6 receptors, for the …

Corticosteroids for diabetic macular edema

J Chawan-Saad, M Wu, A Wu, L Wu - Taiwan Journal of …, 2019 - journals.lww.com
Diabetic macular edema (DME) is a chronic condition with a multifactorial pathogenesis.
Vascular endothelial growth factor (VEGF) and several inflammatory mediators are …