Abstract Serotonin (5-hydroxytryptamine or 5-HT) is a multifunctional bioamine with
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …

The microbiota-gut-brain axis transmits bidirectional communication between the gut and
the central nervous system and links the emotional and cognitive centers of the brain with …

Autonomous regulation of the intestine requires the combined activity of functionally distinct
neurons of the enteric nervous system (ENS). However, the variety of enteric neuron types …

Covers all aspects of the structure, function, neurochemistry, transmitter identification and
development of the enteric nervous system This book brings together extensive knowledge …

Intrinsic primary afferent neurons (IPANs) of the enteric nervous system are quite different
from all other peripheral neurons. The IPANs are transducers of physiological stimuli …

The definition of the nerve cell types of the myenteric plexus of the mouse small intestine has
become important, as more researchers turn to the use of mice with genetic mutations to …

Background and Aims Bowel function requires coordinated activity of diverse enteric neuron
subtypes. Our aim was to define gene expression in these neuron subtypes to facilitate …

Of all the organ systems in the body, the gastrointestinal tract is the most complicated in
terms of the numbers of structures involved, each with different functions, and the numbers …

The enteric nervous system controls a variety of gastrointestinal functions including intestinal
motility. The minimal neuronal circuit necessary to direct peristalsis is well-characterized but …

Cell therapy has the potential to treat gastrointestinal motility disorders caused by diseases
of the enteric nervous system. Many studies have demonstrated that various stem/progenitor …