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[HTML][HTML] Pathology and pathogenesis of metabolic dysfunction-associated steatotic liver disease-associated hepatic tumors
Y Takahashi, E Dungubat, H Kusano, T Fukusato - Biomedicines, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive fat accumulation in
the livers of patients without a history of alcohol abuse. It is classified as either simple …
the livers of patients without a history of alcohol abuse. It is classified as either simple …
miR-22 gene therapy treats HCC by promoting anti-tumor immunity and enhancing metabolism
MicroRNA-22 (miR-22) can be induced by beneficial metabolites that have metabolic and
immune effects, including retinoic acids, bile acids, vitamin D 3, and short-chain fatty acids …
immune effects, including retinoic acids, bile acids, vitamin D 3, and short-chain fatty acids …
[HTML][HTML] Overexpression of Galectin-1 and Galectin-3 in hepatocellular carcinoma
Galectins (Gals) are evolutionarily conserved proteins that bind to β-galactoside containing
glycans. Abnormal expression of Gals is associated with the development, progression, and …
glycans. Abnormal expression of Gals is associated with the development, progression, and …
Hsa-miR-22-3p inhibits liver cancer cell EMT and cell migration/invasion by indirectly regulating SPRY2
S Cui, Y Chen, Y Guo, X Wang, D Chen - PLoS One, 2023 - journals.plos.org
The general mechanism for microRNAs to play biological function is through their inhibition
on the expression of their target genes. In cancer, microRNAs may accelerate cell …
on the expression of their target genes. In cancer, microRNAs may accelerate cell …
MicroRNA-22-3p displaces critical host factors from the 5′ UTR and inhibits the translation of Coxsackievirus B3 RNA
ABSTRACT Coxsackievirus B3 (CVB3) is known to cause acute myocarditis and pancreatitis
in humans. We investigated the microRNAs (miRNAs) that can potentially govern the viral …
in humans. We investigated the microRNAs (miRNAs) that can potentially govern the viral …
[HTML][HTML] Free fatty acid-induced miR-22 inhibits gluconeogenesis via SIRT-1-mediated PGC-1α expression in nonalcoholic fatty liver disease
A bstract Background and aims Free fatty acids (FFAs) are one of the important regulators of
the progression of nonalcoholic fatty liver disease. The FFAs are shown to modulate the …
the progression of nonalcoholic fatty liver disease. The FFAs are shown to modulate the …
An immunocompetent environment unravels the proto-oncogenic role of miR-22
Simple Summary Through their regulatory activity of gene expression, microRNAs have
been heavily implicated in the genesis of cancer. They can act both as promoters …
been heavily implicated in the genesis of cancer. They can act both as promoters …
[HTML][HTML] MiR-22 deficiency fosters hepatocellular carcinoma development in fatty liver
MiR-22 is mostly considered as a hepatic tumor-suppressor microRNA based on in vitro
analyses. Yet, whether miR-22 exerts a tumor-suppressive function in the liver has not been …
analyses. Yet, whether miR-22 exerts a tumor-suppressive function in the liver has not been …
[HTML][HTML] The Role of microRNA-22 in Metabolism
S Tomasini, P Vigo, F Margiotta… - International …, 2025 - pmc.ncbi.nlm.nih.gov
microRNA-22 (miR-22) plays a pivotal role in the regulation of metabolic processes and has
emerged as a therapeutic target in metabolic disorders, including obesity, type 2 diabetes …
emerged as a therapeutic target in metabolic disorders, including obesity, type 2 diabetes …
Evaluation of the relationship between miRNA-22-3p and Gal-9 levels in glioblastoma
Z Barut, FT Akdeniz - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: Glioblastoma, the most prevalent primary malignant brain tumor, is
significantly impacted by molecular mechanisms, including the function of microRNAs and …
significantly impacted by molecular mechanisms, including the function of microRNAs and …