Molecular mechanisms of morphine tolerance and dependence; novel insights and future perspectives

I Badshah, M Anwar, B Murtaza, MI Khan - Molecular and Cellular …, 2024 - Springer
Drug addiction is a devastating condition that poses a serious burden on the society. The
use of some drugs like morphine for their tremendous analgesic properties is also …

Embracing lipidomics at single-cell resolution: Promises and pitfalls

Z Wang, M Cao, SM Lam, G Shui - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Technological innovations have transformed the way scientists approach biological and
clinical questions, transiting from conventional ensemble assays in bulk to emphasize on the …

Training deep neural density estimators to identify mechanistic models of neural dynamics

PJ Gonçalves, JM Lueckmann, M Deistler… - Elife, 2020 - elifesciences.org
Mechanistic modeling in neuroscience aims to explain observed phenomena in terms of
underlying causes. However, determining which model parameters agree with complex and …

[HTML][HTML] Real-time selective detection of dopamine and serotonin at nanomolar concentration from complex in vitro systems

S Rantataro, I Parkkinen, M Airavaara… - Biosensors and …, 2023 - Elsevier
Electrochemical sensors provide means for real-time monitoring of neurotransmitter release
events, which is a relatively easy process in simple electrolytes. However, this does not …

Neuron devices: emerging prospects in neural interfaces and recognition

Y Wang, S Liu, H Wang, Y Zhao… - Microsystems & …, 2022 - nature.com
Neuron interface devices can be used to explore the relationships between neuron firing
and synaptic transmission, as well as to diagnose and treat neurological disorders, such as …

In vivo whole-cell patch-clamp methods: recent technical progress and future perspectives

A Noguchi, Y Ikegaya, N Matsumoto - Sensors, 2021 - mdpi.com
Brain functions are fundamental for the survival of organisms, and they are supported by
neural circuits consisting of a variety of neurons. To investigate the function of neurons at the …

Emerging diversity of channelrhodopsins and their structure-function relationships

EG Govorunova, OA Sineshchekov… - Frontiers in cellular …, 2022 - frontiersin.org
Cation and anion channelrhodopsins (CCRs and ACRs, respectively) from phototactic algae
have become widely used as genetically encoded molecular tools to control cell membrane …

Nanotechnology: new opportunities for the development of patch‐clamps

J Gao, C Liao, S Liu, T **a, G Jiang - Journal of nanobiotechnology, 2021 - Springer
The patch-clamp technique is one of the best approaches to investigate neural excitability.
Impressive improvements towards the automation of the patch-clamp technique have been …

Nonlinear responses in a neural network under spatial electromagnetic radiation

Y Guo, Y **e, J Ma - Physica A: Statistical Mechanics and its Applications, 2023 - Elsevier
Biological neurons are clustered and functional synapses are created to propagate electric
signals accompanying with formation of spatial patterns in the neural network. From physical …

[HTML][HTML] Application of Non-invasive Micro-test Technology (NMT) in environmental fields: A comprehensive review

M Han, H Yang, G Yu, P Jiang, S You, L Zhang… - Ecotoxicology and …, 2022 - Elsevier
Abstract Non-invasive Micro-test Technology (NMT) is a selective microelectrode technique
which can detect the flux rates and three-dimensional motion directions of ions or molecules …