Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)

J Wu, X Wang, Q Wang, Z Lou, S Li, Y Zhu… - Chemical Society …, 2019 - pubs.rsc.org
Nanozymes are nanomaterials with enzyme-like characteristics (Chem. Soc. Rev., 2013, 42,
6060–6093). They have been developed to address the limitations of natural enzymes and …

Nanozymes: A clear definition with fuzzy edges

H Wei, L Gao, K Fan, J Liu, J He, X Qu, S Dong… - Nano Today, 2021 - Elsevier
Recently, an editorial in ACS Catalysis entitled 'nano-apples and orange-zymes' questioned
whether or not the term “nanozyme” was appropriate [1]. When a new term in science is …

Living macrophage-delivered tetrapod PdH nanoenzyme for targeted atherosclerosis management by ROS scavenging, hydrogen anti-inflammation, and autophagy …

R Hu, C Dai, C Dong, L Ding, H Huang, Y Chen… - ACS …, 2022 - ACS Publications
Atherosclerosis, driven by chronic inflammation in the artery walls, underlies several severe
cardiovascular diseases. However, currently available anti-inflammatory-based strategies …

In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy

K Fan, J **, L Fan, P Wang, C Zhu, Y Tang, X Xu… - Nature …, 2018 - nature.com
Nanomaterials with intrinsic enzyme-like activities (nanozymes), have been widely used as
artificial enzymes in biomedicine. However, how to control their in vivo performance in a …

Atomic engineering of single-atom nanozymes for enzyme-like catalysis

W Wu, L Huang, E Wang, S Dong - Chemical science, 2020 - pubs.rsc.org
Enzyme mimics, especially nanozymes, play a crucial role in replacing natural enzymes for
diverse applications related to bioanalysis, therapeutics and other enzyme-like catalysis …

[HTML][HTML] Iron oxide nanozyme: a multifunctional enzyme mimetic for biomedical applications

L Gao, K Fan, X Yan - Theranostics, 2017 - ncbi.nlm.nih.gov
Iron oxide nanoparticles have been widely used in many important fields due to their
excellent nanoscale physical properties, such as magnetism/superparamagnetism. They are …

Surface modification of nanozymes

B Liu, J Liu - Nano Research, 2017 - Springer
Nanoparticles and proteins are similar in a number of aspects, and using nanoparticles to
mimic the catalytic function of enzymes is an interesting yet challenging task. Impressive …

Biodegradation-mediated enzymatic activity-tunable molybdenum oxide nanourchins for tumor-specific cascade catalytic therapy

X Hu, F Li, F **a, X Guo, N Wang, L Liang… - Journal of the …, 2019 - ACS Publications
Recent advances in nanomedicine have facilitated the development of potent nanomaterials
with intrinsic enzyme-like activities (nanozymes) for cancer therapy. However, it remains a …

Optimization of Fe 3 O 4 nanozyme activity via single amino acid modification mimicking an enzyme active site

K Fan, H Wang, J **, Q Liu, X Meng, D Duan… - Chemical …, 2017 - pubs.rsc.org
The Fe3O4 nanozyme was the first reported nanoparticle with intrinsic peroxidase-like
activity and has been widely used in biomedicine. To optimize its catalytic activity, we …