The spectrum of GATA2 deficiency syndrome
KR Calvo, DD Hickstein - Blood, 2023 - ashpublications.org
Inherited or de novo germ line heterozygous mutations in the gene encoding the
transcription factor GATA2 lead to its deficiency. This results in a constellation of clinical …
transcription factor GATA2 lead to its deficiency. This results in a constellation of clinical …
GATA 2 deficiency: focus on immune system impairment
GATA2 deficiency is a disease with a broad spectrum of clinical presentation, ranging from
lymphedema, deafness, pulmonary dysfunction to miscarriage and urogenital anomalies …
lymphedema, deafness, pulmonary dysfunction to miscarriage and urogenital anomalies …
LncRNA FOXP4-AS1 promotes the progression of esophageal squamous cell carcinoma by interacting with MLL2/H3K4me3 to upregulate FOXP4
Y Niu, G Wang, Y Li, W Guo, Y Guo, Z Dong - Frontiers in Oncology, 2021 - frontiersin.org
Malignant tumors are a grave threat to human health. Esophageal squamous cell carcinoma
(ESCC) is a common gastrointestinal malignant tumor. China has a high incidence of ESCC …
(ESCC) is a common gastrointestinal malignant tumor. China has a high incidence of ESCC …
Long noncoding RNA GATA2AS influences human erythropoiesis by transcription factor and chromatin landscape modulation
G Liu, J Kim, N Nguyen, L Zhou, A Dean - Blood, 2024 - ashpublications.org
Long noncoding RNAs (lncRNAs) are extensively expressed in eukaryotic cells and have
been revealed to be important for regulating cell differentiation. Many lncRNAs have been …
been revealed to be important for regulating cell differentiation. Many lncRNAs have been …
GATA2 deficiency: predisposition to myeloid malignancy and hematopoietic cell transplantation
RV Rajput, DE Arnold - Current Hematologic Malignancy Reports, 2023 - Springer
Purpose of Review GATA2 deficiency is a haploinsufficiency syndrome associated with a
wide spectrum of disease, including severe monocytopenia and B and NK lymphopenia …
wide spectrum of disease, including severe monocytopenia and B and NK lymphopenia …
Cell fate determination is associated with changes in competing transcriptional units in the human GATA1 and GATA2 lineage-determining transcription factors
The GATA1 and GATA2 transcription factors play a central role in early cell fate decisions in
hematopoietic progenitor cells. Although the switch from GATA2 to GATA1 occupancy at …
hematopoietic progenitor cells. Although the switch from GATA2 to GATA1 occupancy at …
GATA2: sense and (anti) sensibility
MD Gibbons, J Bungert - Blood, 2024 - ashpublications.org
Transcription factor GATA2 plays an important role in the maintenance of hematopoietic
stem cells and in the specification of hematopoietic cell lineages derived from common …
stem cells and in the specification of hematopoietic cell lineages derived from common …