HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment

D Saylor, AM Dickens, N Sacktor, N Haughey… - Nature Reviews …, 2016 - nature.com
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …

Advancing global health and strengthening the HIV response in the era of the Sustainable Development Goals: the International AIDS Society—Lancet Commission

LG Bekker, G Alleyne, S Baral, J Cepeda, D Daskalakis… - The Lancet, 2018 - thelancet.com
Executive summary Inspired by unprecedented improvements in human health and
development in recent decades, our world has embarked on a quest that only a generation …

Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis

Y Wang, M Liu, Q Lu, M Farrell, JM Lappin, J Shi, L Lu… - Neurology, 2020 - AAN Enterprises
Objective To characterize the prevalence and burden of HIV-associated neurocognitive
disorder (HAND) and assess associated factors in the global population with HIV. Methods …

HIV-associated neurocognitive disorder

DB Clifford, BM Ances - The Lancet infectious diseases, 2013 - thelancet.com
Neurological involvement in HIV is often associated with cognitive impairment. Although
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …

HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment

C Eggers, G Arendt, K Hahn, IW Husstedt… - Journal of …, 2017 - Springer
The modern antiretroviral treatment of human immunodeficiency virus (HIV-1) infection has
considerably lowered the incidence of opportunistic infections. With the exception of the …

Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications

S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …

The prevalence of Frascati-criteria-based HIV-associated neurocognitive disorder (HAND) in HIV-infected adults: a systematic review and meta-analysis

J Wei, J Hou, B Su, T Jiang, C Guo, W Wang… - Frontiers in …, 2020 - frontiersin.org
Background: The HIV associated mortality is decreasing in most countries due to the
widespread use of antiretroviral therapy. However, HIV-associated neurocognitive disorder …

Residual immune dysregulation syndrome in treated HIV infection

MM Lederman, NT Funderburg, RP Sekaly… - Advances in …, 2013 - Elsevier
Antiretroviral therapy has revolutionized the course of HIV infection, improving immune
function and decreasing dramatically the mortality and morbidity due to the opportunistic …

Central nervous system complications in HIV disease: HIV-associated neurocognitive disorder

S Letendre - Topics in antiviral medicine, 2016 - pmc.ncbi.nlm.nih.gov
HIV-associated neurocognitive disorder (HAND) is the result of neural damage caused by
HIV replication and immune activation. Potent antiretroviral therapy has reduced the …

Monocyte/macrophages and their role in HIV neuropathogenesis

TH Burdo, A Lackner, KC Williams - Immunological reviews, 2013 - Wiley Online Library
Neurological sequelae of human immunodeficiency virus (HIV) infection have been and
remain a significant problem. Monocytes and macrophages in humans and monkeys are …