Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Elastic sealants for surgical applications

N Annabi, K Yue, A Tamayol… - European journal of …, 2015 - Elsevier
Sealants have emerged as promising candidates for replacing sutures and staples to
prevent air and liquid leakages during and after the surgeries. Their physical properties and …

Electrical bioadhesive interface for bioelectronics

J Deng, H Yuk, J Wu, CE Varela, X Chen, ET Roche… - Nature materials, 2021 - nature.com
Reliable functions of bioelectronic devices require conformal, stable and conductive
interfaces with biological tissues. Integrating bioelectronic devices with tissues usually relies …

3D printing of robust high‐performance conducting polymer hydrogel‐based electrical bioadhesive interface for soft bioelectronics

J Yu, R Wan, F Tian, J Cao, W Wang, Q Liu, H Yang… - Small, 2024 - Wiley Online Library
Electrical bioadhesive interface (EBI), especially conducting polymer hydrogel (CPH)‐based
EBI, exhibits promising potential applications in various fields, including biomedical devices …

A strongly adhesive hemostatic hydrogel for the repair of arterial and heart bleeds

Y Hong, F Zhou, Y Hua, X Zhang, C Ni, D Pan… - Nature …, 2019 - nature.com
Uncontrollable bleeding is a major problem in surgical procedures and after major trauma.
Existing hemostatic agents poorly control hemorrhaging from traumatic arterial and cardiac …

Hydrogel tapes for fault-tolerant strong wet adhesion

B Xue, J Gu, L Li, W Yu, S Yin, M Qin, Q Jiang… - Nature …, 2021 - nature.com
Fast and strong bio-adhesives are in high demand for many biomedical applications,
including closing wounds in surgeries, fixing implantable devices, and haemostasis …

Heparin-poloxamer thermosensitive hydrogel loaded with bFGF and NGF enhances peripheral nerve regeneration in diabetic rats

R Li, Y Li, Y Wu, Y Zhao, H Chen, Y Yuan, K Xu… - Biomaterials, 2018 - Elsevier
Peripheral nerve injury (PNI) is a major burden to society with limited therapeutic options,
and novel biomaterials have great potential for shifting the current paradigm of treatment …

Stem Cell‐Niche Engineering via Multifunctional Hydrogel Potentiates Stem Cell Therapies for Inflammatory Bone Loss

G Li, Z Li, L Li, S Liu, P Wu, M Zhou, C Li… - Advanced Functional …, 2023 - Wiley Online Library
Effective therapies capable of simultaneously inhibiting inflammation and promoting bone
healing remain to be developed for inflammatory bone disease. Stem cell therapies hold …

A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects

N Lang, MJ Pereira, Y Lee, I Friehs… - Science translational …, 2014 - science.org
Currently, there are no clinically approved surgical glues that are nontoxic, bind strongly to
tissue, and work well within wet and highly dynamic environments within the body. This is …

Sustained delivery of MMP-9 siRNA via thermosensitive hydrogel accelerates diabetic wound healing

B Lan, L Zhang, L Yang, J Wu, N Li, C Pan… - Journal of …, 2021 - Springer
Excessive expression of matrix metalloproteinase 9 (MMP-9) impedes healing of diabetic
chronic wounds, thus wound dressing that could effectively inhibit the expression of MMP-9 …