[HTML][HTML] Antibacterial and Antifungal Activities of Linear and Cyclic Peptides Containing Arginine, Tryptophan, and Diphenylalanine

D Salehi, EHM Mohammed, NM Helmy, K Parang - Antibiotics, 2025‏ - mdpi.com
Background. We have previously reported peptides composed of sequential arginine (R)
residues paired with tryptophan (W) or 3, 3-diphenyl-L-alanine residues (Dip), such as cyclic …

Impact of Stereochemical Replacement on the Activity and Selectivity of Membrane-Active Cationic Cyclic Peptides with Broad-Spectrum Antibacterial and Antifungal …

S Lohan, AG Konshina, EHM Mohammed, NM Helmy… - 2025‏ - chemrxiv.org
Herein, we report a library of 7-mer macrocyclic peptides designed by systematically
replacing one, multiple, or all L-amino acids with their D-isomers in our previously identified …