D-Amino acid oxidase (DAAO) is an FAD-containing flavoenzyme that catalyzes with
absolute stereoselectivity the oxidative deamination of all natural D-amino acids, the only …

Amino acids (AAs) of nutritional importance exist as L-isomers, while D-isomeric form of AAs
is common constituent of bacterial cell wall. The presence of D-amino acids in foods is …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder involving an
extensive loss of motoneurons. Aberrant excitability of motoneurons has been implicated in …

D-amino acid oxidase (DAO) is a flavoenzyme that metabolizes certain D-amino acids,
notably the endogenous N-methyl D-aspartate receptor (NMDAR) co-agonist, D-serine. As …

Due to its stringent stereospecificity, D‐amino acid oxidase (DAAO) has made it very easy to
synthesize L‐amino acids. However, the low activity of the wild‐type enzyme toward …

Schizophrenia has been conceptualized as a neurodevelopmental disorder with synaptic
alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of …

Imaging is increasingly used to detect and monitor bacterial infection. Both anatomic (X-rays,
computed tomography, ultrasound, and MRI) and nuclear medicine ([111In]-WBC …

Schizophrenia is a severe mental illness that affects~ 1% of the world's population. It is
clinically characterized by positive, negative, and cognitive symptoms. Currently available …

Abstract d-Alanine (d-Ala) is an unusual endogenous amino acid present in invertebrates
and vertebrates. Compared to its l-isomer, the characterization of d-Ala is challenging …

Over the past years, accumulating evidence has indicated that d-serine is the endogenous
ligand for the glycine-modulatory binding site on the NR1 subunit of N-methyl-d-aspartate …