RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy

A Sheikh, S Md, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: An up-to-date perspective

DE Nayab, F Din, H Ali, WA Kausar, S Urooj… - Journal of …, 2023 - Springer
Neurons and their connecting axons gradually degenerate in neurodegenerative diseases
(NDs), leading to dysfunctionality of the neuronal cells and eventually their death. Drug …

Exploring the role of nanomedicines for the therapeutic approach of central nervous system dysfunction: At a glance

MM Rhaman, MR Islam, S Akash, M Mim… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent decades, research scientists, molecular biologists, and pharmacologists have
placed a strong emphasis on cutting-edge nanostructured materials technologies to …

Lipid-coated MCM-41 mesoporous silica nanoparticles loaded with berberine improved inhibition of acetylcholine esterase and amyloid formation

AK Singh, SS Singh, AS Rathore… - ACS Biomaterials …, 2021 - ACS Publications
Selective permeability of the blood–brain barrier limits effective treatment of
neurodegenerative disorders. In the present study, brain-targeted lipid-coated mesoporous …

Dendrimer: An update on recent developments and future opportunities for the brain tumors diagnosis and treatment

M Kaurav, S Ruhi, HA Al-Goshae, AK Jeppu… - Frontiers in …, 2023 - frontiersin.org
A brain tumor is an uncontrolled cell proliferation, a mass of tissue composed of cells that
grow and divide abnormally and appear to be uncontrollable by the processes that normally …

Nanocarrier mediated drug delivery as an impeccable therapeutic approach against Alzheimer's disease

R Taliyan, V Kakoty, KC Sarathlal… - Journal of controlled …, 2022 - Elsevier
For the past several years, dementia, is one of the predominantly observed groups of
symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …

[HTML][HTML] Dendrimers and derivatives as multifunctional nanotherapeutics for Alzheimer's disease

DA Moreira, SD Santos, V Leiro, AP Pêgo - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. It affects more than 30
million people worldwide and costs over US $1.3 trillion annually. AD is characterized by the …

The importance of pre-formulation studies and of 3D-printed nasal casts in the success of a pharmaceutical product intended for nose-to-brain delivery

L Deruyver, C Rigaut, P Lambert, B Haut… - Advanced drug delivery …, 2021 - Elsevier
This review aims to cement three hot topics in drug delivery:(a) the pre-formulation of new
products intended for nose-to-brain delivery;(b) the development of nasal casts for studying …

Current Overview on the Use of Nanosized Drug Delivery Systems in the Treatment of Neurodegenerative Diseases

O Ozceylan, Z Sezgin-Bayindir - ACS omega, 2024 - ACS Publications
Neurodegenerative diseases, encompassing conditions such as Alzheimer's disease,
Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, prion disease, and …

In vitro profiling and molecular dynamics simulation studies of berberine loaded MCM-41 mesoporous silica nanoparticles to prevent neuronal apoptosis

AK Singh, S Singh, T Minocha, SK Yadav… - Nanoscale …, 2024 - pubs.rsc.org
Neuronal loss in Alzheimer's disease has been reported to display features of apoptosis,
pyroptosis (programmed necrosis), or necroptosis. This study thoroughly examines the …