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Lipid-based emulsion drug delivery systems—A comprehensive review
Lipid-based emulsion system—a subcategory of emulsion technology, has emerged as an
enticing option to improve the solubility of the steadily rising water-insoluble candidates …
enticing option to improve the solubility of the steadily rising water-insoluble candidates …
Co-processed excipients: Recent advances and future perspective
The demands on the functionality of excipients are increasing day by day because of the
emergence of high-speed tableting machines and the use of direct compression methods for …
emergence of high-speed tableting machines and the use of direct compression methods for …
Investigating the role of the reduced solubility of the pirfenidone–fumaric acid cocrystal in sustaining the release rate from its tablet dosage form by conducting …
Pirfenidone (PFD) is the first pharmacological agent approved by the US Food and Drug
Administration (FDA) in 2014 for the treatment of idiopathic pulmonary fibrosis (IPF). The …
Administration (FDA) in 2014 for the treatment of idiopathic pulmonary fibrosis (IPF). The …
Mannitol-coated hydroxypropyl methylcellulose as an alternative directly compressible controlled release excipient
CYX Kang, WC Foo, KH Lam, KT Chow, YS Lui… - International journal of …, 2024 - Elsevier
One of the most common forms of controlled release technology for oral drug delivery
comprises an active ingredient dispersed in a hydrophilic matrix forming polymer such as …
comprises an active ingredient dispersed in a hydrophilic matrix forming polymer such as …
Premix technologies for drug delivery: manufacturing, applications, and opportunities in regulatory filing
Active pharmaceutical ingredients (APIs) and excipients can be carefully combined in
premix-based materials before being added to dosage forms, providing a flexible platform …
premix-based materials before being added to dosage forms, providing a flexible platform …
Alginate-based matrix tablets for drug delivery
Introduction As a nature-derived polymer with swelling and gelling properties, alginate has
found wide biopharma-relevant applications. However, there is comparatively limited …
found wide biopharma-relevant applications. However, there is comparatively limited …
A comprehensive understanding of disintegrants and disintegration quantification techniques: From the perspective of tablet microstructure
Z Liu, C Shi, Y Fang, H Zhao, Y Mu, L Zhao… - Journal of Drug Delivery …, 2023 - Elsevier
Disintegration is the process where tablets break down into small particles in a liquid
medium. Sufficient disintegration of tablets is conducive to the rapid dissolution of drugs and …
medium. Sufficient disintegration of tablets is conducive to the rapid dissolution of drugs and …
[HTML][HTML] Mannitol-Coated Hydroxypropyl Methylcellulose as a Directly Compressible Controlled Release Excipient for Moisture-Sensitive Drugs: A Stability …
CYX Kang, KT Chow, YS Lui, A Salome, B Boit… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: Hydroxypropyl methylcellulose (HPMC) is one of the most
commonly used hydrophilic polymers in formulations of matrix tablets for controlled release …
commonly used hydrophilic polymers in formulations of matrix tablets for controlled release …
Formulation of taste-masked orodispersible famotidine tablets by sequential spray drying and direct compression–Bitterness evaluation
Since famotidine (FA) is prescribed for gastrointestinal diseases orodispersible tablets could
contribute to patients' compliance. Its bitter taste and poor compressibility pose formulation …
contribute to patients' compliance. Its bitter taste and poor compressibility pose formulation …
Using twin-screw melt granulation to co-process mannitol and hydroxypropylcellulose
With the advent of continuous manufacturing, twin-screw melt granulation has attracted
interest in the pharmaceutical industry as a method for co-processing excipients and …
interest in the pharmaceutical industry as a method for co-processing excipients and …