Lipid-based emulsion drug delivery systems—A comprehensive review

M Dhaval, P Vaghela, K Patel, K Sojitra, M Patel… - Drug delivery and …, 2022 - Springer
Lipid-based emulsion system—a subcategory of emulsion technology, has emerged as an
enticing option to improve the solubility of the steadily rising water-insoluble candidates …

Co-processed excipients: Recent advances and future perspective

V Bhatia, A Dhingra, B Chopra, K Guarve - Journal of Drug Delivery …, 2022 - Elsevier
The demands on the functionality of excipients are increasing day by day because of the
emergence of high-speed tableting machines and the use of direct compression methods for …

Investigating the role of the reduced solubility of the pirfenidone–fumaric acid cocrystal in sustaining the release rate from its tablet dosage form by conducting …

N Kumari, P Roy, S Roy, PK Parmar… - Molecular …, 2022 - ACS Publications
Pirfenidone (PFD) is the first pharmacological agent approved by the US Food and Drug
Administration (FDA) in 2014 for the treatment of idiopathic pulmonary fibrosis (IPF). The …

Mannitol-coated hydroxypropyl methylcellulose as an alternative directly compressible controlled release excipient

CYX Kang, WC Foo, KH Lam, KT Chow, YS Lui… - International journal of …, 2024 - Elsevier
One of the most common forms of controlled release technology for oral drug delivery
comprises an active ingredient dispersed in a hydrophilic matrix forming polymer such as …

Premix technologies for drug delivery: manufacturing, applications, and opportunities in regulatory filing

MK Ashokbhai, LR Sanjay, SK Sah, S Roy, S Kaity - Drug Discovery Today, 2024 - Elsevier
Active pharmaceutical ingredients (APIs) and excipients can be carefully combined in
premix-based materials before being added to dosage forms, providing a flexible platform …

Alginate-based matrix tablets for drug delivery

N Veronica, PWS Heng, CV Liew - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction As a nature-derived polymer with swelling and gelling properties, alginate has
found wide biopharma-relevant applications. However, there is comparatively limited …

A comprehensive understanding of disintegrants and disintegration quantification techniques: From the perspective of tablet microstructure

Z Liu, C Shi, Y Fang, H Zhao, Y Mu, L Zhao… - Journal of Drug Delivery …, 2023 - Elsevier
Disintegration is the process where tablets break down into small particles in a liquid
medium. Sufficient disintegration of tablets is conducive to the rapid dissolution of drugs and …

[HTML][HTML] Mannitol-Coated Hydroxypropyl Methylcellulose as a Directly Compressible Controlled Release Excipient for Moisture-Sensitive Drugs: A Stability …

CYX Kang, KT Chow, YS Lui, A Salome, B Boit… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: Hydroxypropyl methylcellulose (HPMC) is one of the most
commonly used hydrophilic polymers in formulations of matrix tablets for controlled release …

Formulation of taste-masked orodispersible famotidine tablets by sequential spray drying and direct compression–Bitterness evaluation

FM Stavras, I Partheniadis, I Nikolakakis - Journal of Drug Delivery Science …, 2023 - Elsevier
Since famotidine (FA) is prescribed for gastrointestinal diseases orodispersible tablets could
contribute to patients' compliance. Its bitter taste and poor compressibility pose formulation …

Using twin-screw melt granulation to co-process mannitol and hydroxypropylcellulose

A Pradhan, M Costello, F Yang, V Bi, T Durig… - Journal of Drug Delivery …, 2022 - Elsevier
With the advent of continuous manufacturing, twin-screw melt granulation has attracted
interest in the pharmaceutical industry as a method for co-processing excipients and …