VHH Structural Modelling Approaches: A Critical Review
P Vishwakarma, AM Vattekatte, N Shinada… - International Journal of …, 2022 - mdpi.com
VHH, ie, VH domains of camelid single-chain antibodies, are very promising therapeutic
agents due to their significant physicochemical advantages compared to classical …
agents due to their significant physicochemical advantages compared to classical …
A Perspective on the (Rise and Fall of) Protein β-Turns
AG de Brevern - International Journal of Molecular Sciences, 2022 - mdpi.com
The β-turn is the third defined secondary structure after the α-helix and the β-sheet. The β-
turns were described more than 50 years ago and account for more than 20% of protein …
turns were described more than 50 years ago and account for more than 20% of protein …
Alphafold2 update and perspectives
Access to the three-dimensional (3D) structural information of macromolecules is of major
interest in both fundamental and applied research. Obtaining this experimental data can be …
interest in both fundamental and applied research. Obtaining this experimental data can be …
Emerging role of carbonyl–carbonyl interactions in the classification of beta turns
Carbonyl–carbonyl interactions in peptides and proteins attracted considerable interest in
recent years. Here, we report a survey of carbonyl–carbonyl interactions in cyclic peptides …
recent years. Here, we report a survey of carbonyl–carbonyl interactions in cyclic peptides …
An agnostic analysis of the human AlphaFold2 proteome using local protein conformations
AG de Brevern - Biochimie, 2023 - Elsevier
Abstract Knowledge of the 3D structure of proteins is a valuable asset for understanding
their precise biological mechanisms. However, the cost of production of 3D structures and …
their precise biological mechanisms. However, the cost of production of 3D structures and …
Engineering Matrix-Free Drug Protein Nanoparticles with Promising Penetration through Biobarriers for Treating Corneal Neovascularization
H Xu, B Mao, S Ni, X **, and dynamics …
Drug-resistant fungal infections pose a formidable challenge in healthcare, attributed to
ergosterol production as a key mechanism of resistance. It is therefore imperative to target …
ergosterol production as a key mechanism of resistance. It is therefore imperative to target …
Structural and dynamic differences between calreticulin mutants associated with essential thrombocythemia
Essential thrombocythemia (ET) is a blood cancer. ET is characterized by an overproduction
of platelets that can lead to thrombosis formation. Platelet overproduction occurs in …
of platelets that can lead to thrombosis formation. Platelet overproduction occurs in …