The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …

Ascorbic acid is a key antioxidant of the Central Nervous System (CNS). Under brain activity,
ascorbic acid is released from glial reservoirs to the synaptic cleft, where it is taken up by …

Ascorbic acid (AA) is a water-soluble vitamin (C) found in all bodily organs. Most mammals
synthesize it, humans are required to eat it, but all mammals need it for healthy functioning …

Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks.
Numerous studies have suggested a strong correlation between oxidative stress and …

Objective Role of apoptosis and neuroinflammation have been well established in the
pathogenesis of epilepsy. It has been reported that the activation of nuclear factor-erythroid …

There is an unmet need to develop alternative therapeutic strategies to not only restrain
seizures but also to alleviate the underlying pathologies and sequelae. Berberine (BBR), an …

Vascular dementia (VaD) is a progressive cognitive impairment caused by a reduced blood
supply to the brain. Chronic cerebral hypoperfusion (CCH) is one cause of VaD; it induces …

Compelling evidence has shown that exposure to anesthetics used in the clinic can cause
neurodegeneration in the mammalian develo** brain, but the basis of this is not clear …

Background/Aims: Ginsenoside Rb1 (Rb1) has been reported to have varieties of
neuroprotective effects. This study aimed to evaluate the effects of Rb1 on pentylenetetrazol …

Ethanol is the most common human teratogen, and its consumption during pregnancy can
produce a wide range of abnormalities in infants known as fetal alcohol spectrum disorder …