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Opioid-driven disruption of the septal complex reveals a role for neurotensin-expressing neurons in withdrawal
Because opioid withdrawal is an intensely aversive experience, persons with opioid use
disorder (OUD) often relapse to avoid it. The lateral septum (LS) is a forebrain structure that …
disorder (OUD) often relapse to avoid it. The lateral septum (LS) is a forebrain structure that …
Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system
H Haun, R Hernandez, L Yan, M Flanigan, O Hon… - bioRxiv, 2024 - biorxiv.org
High intensity alcohol drinking during binge episodes overwhelmingly contributes to the
socioeconomic burden created by Alcohol Use Disorders (AUD). Novel interventions are …
socioeconomic burden created by Alcohol Use Disorders (AUD). Novel interventions are …
Orexinergic lateral hypothalamus (LH) projections to medial septum (MS) modulate ethanol-induced sedation in male and female mice and binge-like ethanol drinking …
Orexin in both the lateral hypothalamus (LH) and medial septum (MS) is involved in sleep-
and consciousness-related conditions. Since orexin modulates the intoxicating as well as …
and consciousness-related conditions. Since orexin modulates the intoxicating as well as …