Abstract p53 is a transcription factor that suppresses tumor growth through regulation of
dozens of target genes with diverse biological functions. The activity of this master …

MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …

Circular RNAs (circRNAs) represent a class of widespread and diverse endogenous RNAs
that may regulate gene expression in eukaryotes. However, the regulation and function of …

The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …

Background Several of the thousands of human long noncoding RNAs (lncRNAs) have
been functionally characterized, yet their potential involvement in hepatocellular carcinoma …

Accumulating evidence indicates that circular RNAs (circRNAs) are abundant in the human
transcriptome. However, their involvement in biological processes, including pluripotency …

Mammalian long intergenic noncoding RNAs (lincRNAs) are best known for modulating
transcription. Here we report a posttranscriptional function for lincRNA-p21 as a modulator of …

Background & Aims Pancreatic cancer has the highest prevalence of cancer-associated
cachexia among all cancers. ZIP4 promotes pancreatic cancer progression by regulating …

In recent years, microRNAs (miRNAs) have been identified as mediators of tumour
suppression and stress responses exerted by the p53 tumour suppressor. p53-regulated …

MicroRNAs (miRNAs) are key regulators of gene expression. They are conserved across
species, expressed across cell types, and active against a large proportion of the …