Fermentation, the microbial degradation of organic compounds without net oxidation, is an
important process in the global carbon cycle and is also exploited worldwide for the …

In the era of sustainable development, the use of cell factories to produce various
compounds by fermentation has attracted extensive attention; however, industrial …

The genus Pseudomonas comprises approximately 200 species with numerous isolates that
are common inhabitants of soil, water, and vegetation and has been of particular interest for …

A novel regulatory mechanism for control of the ubiquitous 2-oxoglutarate dehydrogenase
complex (ODH), a key enzyme of the tricarboxylic acid cycle, was discovered in the …

Abstract Systems-level design of cell metabolism is becoming increasingly important for
renewable production of fuels, chemicals, and drugs. Computational models are improving …

Lactic acid bacteria (LAB) have a long tradition of use in the food industry, and the number
and diversity of their applications has increased considerably over the years. Traditionally …

We recently showed that the activity of the 2-oxoglutarate dehydrogenase complex (ODHC)
in Corynebacterium glutamicum is controlled by a novel regulatory mechanism that involves …

Since its discovery 60 years ago, Corynebacterium glutamicum has evolved into a
workhorse for industrial biotechnology. Traditionally well known for its remarkable capacity …

Background In silico genome-scale metabolic models enable the analysis of the
characteristics of metabolic systems of organisms. In this study, we reconstructed a genome …

Corynebacterium glutamicum is widely used for the biotechnological production of amino
acids. Amino acid producing strains have been improved classically by mutagenesis and …