MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs that can post-
transcriptionally regulate the expression of various oncogenes and tumor suppressor genes …

Aim Approximately 20% of patients treated with neoadjuvant chemoradiotherapy (nCRT) for
locally advanced rectal cancer achieve a pathological complete response (p CR) while the …

Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …

Colorectal cancer (CRC) is a major contributor to cancer-associated morbidity worldwide
and over one-third of CRC is located in the rectum. Neoadjuvant chemoradiotherapy (nCRT) …

Objective To validate the mechanism by which miR-21-5p mediates autophagy in drug-
resistant cells in hepatocellular carcinoma (HCC), aggravating sorafenib resistance and …

Background Colorectal cancer (CRC) is one of the most common gastrointestinal
malignancies with a significant mortality rate. Despite the great advances in cancer …

Chemotherapy and targeted therapy are the main options for andvanced colorectal cancer
(CRC). However, resistance to these therapies is a major challenge in the clinic …

New anticancer agents with lower toxicity have been always urged because of drug
resistance associated with overused chemotherapy agents. In this study, steviol, a colonic …

In the past decade, miRNAs have been extensively attracted the scientist's attentions as
tumor suppressors or oncogenes that have been implicated in tumor progression …

Abstract MiR-21-5p has been identified as an oncogene to enhance human tumor
progression. Here, we explored the mechanism by which miR-21-5p regulated progression …