[PDF][PDF] Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Diffraction (X-ray, neutron and electron) and electron cryo-microscopy are powerful methods
to determine three-dimensional macromolecular structures, which are required to …
to determine three-dimensional macromolecular structures, which are required to …
Virological characteristics of the SARS-CoV-2 Omicron BA. 2 subvariants, including BA. 4 and BA. 5
After the global spread of the SARS-CoV-2 Omicron BA. 2, some BA. 2 subvariants,
including BA. 2.9. 1, BA. 2.11, BA. 2.12. 1, BA. 4, and BA. 5, emerged in multiple countries …
including BA. 2.9. 1, BA. 2.11, BA. 2.12. 1, BA. 4, and BA. 5, emerged in multiple countries …
Structural evidence for intermediates during O2 formation in photosystem II
In natural photosynthesis, the light-driven splitting of water into electrons, protons and
molecular oxygen forms the first step of the solar-to-chemical energy conversion process …
molecular oxygen forms the first step of the solar-to-chemical energy conversion process …
Structures of the σ2 receptor enable docking for bioactive ligand discovery
The σ2 receptor has attracted intense interest in cancer imaging, psychiatric disease,
neuropathic pain,–and other areas of biology,. Here we determined the crystal structure of …
neuropathic pain,–and other areas of biology,. Here we determined the crystal structure of …
[HTML][HTML] A crystallographic snapshot of SARS-CoV-2 main protease maturation process
GD Noske, AM Nakamura, VO Gawriljuk… - Journal of Molecular …, 2021 - Elsevier
SARS-CoV-2 is the causative agent of COVID-19. The dimeric form of the viral M pro is
responsible for the cleavage of the viral polyprotein in 11 sites, including its own N and C …
responsible for the cleavage of the viral polyprotein in 11 sites, including its own N and C …
X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the pathogen
that causes COVID-19, produces polyproteins 1a and 1ab that contain, respectively, 11 or …
that causes COVID-19, produces polyproteins 1a and 1ab that contain, respectively, 11 or …
The molecular mechanism of transport by the mitochondrial ADP/ATP carrier
JJ Ruprecht, MS King, T Zögg, AA Aleksandrova… - Cell, 2019 - cell.com
Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP
synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix …
synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix …
Structure of photosystem II and substrate binding at room temperature
Light-induced oxidation of water by photosystem II (PS II) in plants, algae and cyanobacteria
has generated most of the dioxygen in the atmosphere. PS II, a membrane-bound multi …
has generated most of the dioxygen in the atmosphere. PS II, a membrane-bound multi …
Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias
The epidermal growth factor receptor (EGFR) is frequently mutated in human cancer,, and is
an important therapeutic target. EGFR inhibitors have been successful in lung cancer, where …
an important therapeutic target. EGFR inhibitors have been successful in lung cancer, where …
A lysine–cysteine redox switch with an NOS bridge regulates enzyme function
M Wensien, FR von Pappenheim, LM Funk… - Nature, 2021 - nature.com
Disulfide bonds between cysteine residues are important post-translational modifications in
proteins that have critical roles for protein structure and stability, as redox-active catalytic …
proteins that have critical roles for protein structure and stability, as redox-active catalytic …